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Drug discovery and evaluationmethods...

Gralinski, Michael R.

Drug discovery and evaluationmethods in clinical pharmacology /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Drug discovery and evaluationedited by Franz J. Hock, Michael R. Gralinski.
Reminder of title:	methods in clinical pharmacology /
other author:	Hock, Franz J.
Published:	Cham :Springer International Publishing :2020.
Description:	xxiii, 1190 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eReference
Subject:	Drug development.
Online resource:	https://doi.org/10.1007/978-3-319-68864-0
ISBN:	9783319688640$q(electronic bk.)

Drug discovery and evaluationmethods in clinical pharmacology /
Drug discovery and evaluationmethods in clinical pharmacology /[electronic resource] :edited by Franz J. Hock, Michael R. Gralinski. - Second edition. - Cham :Springer International Publishing :2020. - xxiii, 1190 p. :ill., digital ;24 cm.

This is the second edition of a well-received book in the series "Drug Discovery and Evaluation" The completely revised new edition of the volume reflects the current state of the art in Clinical Pharmacology. Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology". For the 2nd edition of this volume, the chapters have been revised and completely updated. A large number of assays were added. New chapters were included, such as pain, addiction, gene therapy, orphan diseases.

ISBN: 9783319688640$q(electronic bk.)

Standard No.: 10.1007/978-3-319-68864-0doiSubjects--Topical Terms:

190608
Drug development.

LC Class. No.: RS420 / .D784 2020

Dewey Class. No.: 615.19

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520 $a This is the second edition of a well-received book in the series "Drug Discovery and Evaluation" The completely revised new edition of the volume reflects the current state of the art in Clinical Pharmacology. Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology". For the 2nd edition of this volume, the chapters have been revised and completely updated. A large number of assays were added. New chapters were included, such as pain, addiction, gene therapy, orphan diseases.
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