國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Molecular targeted radiosensitizerso...

Eke, Iris.

Molecular targeted radiosensitizersopportunities and challenges /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Molecular targeted radiosensitizersedited by Henning Willers, Iris Eke.
其他題名:	opportunities and challenges /
其他作者:	Willers, Henning.
出版者:	Cham :Springer International Publishing :2020.
面頁冊數:	xi, 364 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	CancerRadiotherapy
電子資源:	https://doi.org/10.1007/978-3-030-49701-9
ISBN:	9783030497019$q(electronic bk.)

Molecular targeted radiosensitizersopportunities and challenges /
Molecular targeted radiosensitizersopportunities and challenges /[electronic resource] :edited by Henning Willers, Iris Eke. - Cham :Springer International Publishing :2020. - xi, 364 p. :ill., digital ;24 cm. - Cancer drug discovery and development,2196-9906. - Cancer drug discovery and development..

Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance -- Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index.

Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.

ISBN: 9783030497019$q(electronic bk.)

Standard No.: 10.1007/978-3-030-49701-9doiSubjects--Topical Terms:

876452
Cancer
--Radiotherapy

LC Class. No.: RC271.R3 / M654 2020

Dewey Class. No.: 616.9940642

Molecular targeted radiosensitizersopportunities and challenges /
LDR:03366nmm a2200337 a 4500 001 585432
003 DE-He213
005 20201229094639.0
006 m d
007 cr nn 008maaau
008 210311s2020 sz s 0 eng d
020 $a 9783030497019$q(electronic bk.)
020 $a 9783030497002$q(paper)
024 7 $a 10.1007/978-3-030-49701-9 $2 doi
035 $a 978-3-030-49701-9
040 $a GP $c GP
041 0 $a eng
050 4 $a RC271.R3 $b M654 2020
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 616.9940642 $2 23
090 $a RC271.R3 $b M718 2020
245 0 0 $a Molecular targeted radiosensitizers $h [electronic resource] : $b opportunities and challenges / $c edited by Henning Willers, Iris Eke.
260 $a Cham : $b Springer International Publishing : $b Imprint: Humana, $c 2020.
300 $a xi, 364 p. : $b ill., digital ; $c 24 cm.
490 1 $a Cancer drug discovery and development, $x 2196-9906
505 0 $a Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance -- Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index.
520 $a Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.
650 0 $a Cancer $x Radiotherapy $x Molecular aspects. $3 876452
650 0 $a Radiation-sensitizing agents. $3 286299
650 1 4 $a Cancer Research. $3 273660
650 2 4 $a Radiotherapy. $3 274202
650 2 4 $a Pharmacology/Toxicology. $3 273652
700 1 $a Willers, Henning. $3 876450
700 1 $a Eke, Iris. $3 876451
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
830 0 $a Cancer drug discovery and development. $3 557535
856 4 0 $u https://doi.org/10.1007/978-3-030-49701-9
950 $a Medicine (SpringerNature-11650)