國立高雄大學圖資館 |

Language: English

Back

Single-cell sequencing and methylati...

SpringerLink (Online service)

Single-cell sequencing and methylationmethods and clinical applications /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Single-cell sequencing and methylationedited by Buwei Yu ... [et al.].
Reminder of title:	methods and clinical applications /
other author:	Yu, Buwei.
Published:	Singapore :Springer Singapore :2020.
Description:	viii, 247 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	DNAMethylation.
Online resource:	https://doi.org/10.1007/978-981-15-4494-1
ISBN:	9789811544941$q(electronic bk.)

Single-cell sequencing and methylationmethods and clinical applications /
Single-cell sequencing and methylationmethods and clinical applications /[electronic resource] :edited by Buwei Yu ... [et al.]. - Singapore :Springer Singapore :2020. - viii, 247 p. :ill. (some col.), digital ;24 cm. - Advances in experimental medicine and biology,v.12550065-2598 ;. - Advances in experimental medicine and biology ;946..

Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

ISBN: 9789811544941$q(electronic bk.)

Standard No.: 10.1007/978-981-15-4494-1doiSubjects--Topical Terms:

229553
DNA
--Methylation.

LC Class. No.: QP624.5.M46

Dewey Class. No.: 572.8645

Single-cell sequencing and methylationmethods and clinical applications /
LDR:03226nmm a2200349 a 4500 001 585777
003 DE-He213
005 20201230120406.0
006 m d
007 cr nn 008maaau
008 210323s2020 si s 0 eng d
020 $a 9789811544941$q(electronic bk.)
020 $a 9789811544934$q(paper)
024 7 $a 10.1007/978-981-15-4494-1 $2 doi
035 $a 978-981-15-4494-1
040 $a GP $c GP
041 0 $a eng
050 4 $a QP624.5.M46
072 7 $a MBGR $2 bicssc
072 7 $a SCI049000 $2 bisacsh
072 7 $a MBGR $2 thema
072 7 $a PSD $2 thema
082 0 4 $a 572.8645 $2 23
090 $a QP624.5.M46 $b S617 2020
245 0 0 $a Single-cell sequencing and methylation $h [electronic resource] : $b methods and clinical applications / $c edited by Buwei Yu ... [et al.].
260 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2020.
300 $a viii, 247 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.1255
505 0 $a Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.
520 $a With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.
650 0 $a DNA $x Methylation. $3 229553
650 0 $a Sequence alignment (Bioinformatics) $3 680095
650 0 $a Pathology, Cellular. $3 202379
650 0 $a Cytology. $3 189001
650 1 4 $a Molecular Medicine. $3 273932
650 2 4 $a Bioinformatics. $3 194415
650 2 4 $a Cancer Research. $3 273660
700 1 $a Yu, Buwei. $3 876998
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
830 0 $a Advances in experimental medicine and biology ; $v 946. $3 557559
856 4 0 $u https://doi.org/10.1007/978-981-15-4494-1
950 $a Biomedical and Life Sciences (SpringerNature-11642)