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The practice of consumer exposure as...

Hakkinen, Pertti.

The practice of consumer exposure assessment

Record Type:	Electronic resources : Monograph/item
Title/Author:	The practice of consumer exposure assessmentedited by Gerhard Heinemeyer, Matti Jantunen, Pertti Hakkinen.
other author:	Heinemeyer, Gerhard.
Published:	Cham :Springer International Publishing :2019.
Description:	xxxvi, 584 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Pharmaceutical technology.
Online resource:	https://doi.org/10.1007/978-3-319-96148-4
ISBN:	9783319961484$q(electronic bk.)

The practice of consumer exposure assessment
The practice of consumer exposure assessment[electronic resource] /edited by Gerhard Heinemeyer, Matti Jantunen, Pertti Hakkinen. - Cham :Springer International Publishing :2019. - xxxvi, 584 p. :ill. (some col.), digital ;24 cm.

1. General Introduction -- 2. Major Principles and Concepts of Risk Assessment -- 3. General Aspects of Exposure Evaluation -- 4. Exposure to Substances via Food Consumption -- 5. Exposure to Substances by use of Consumer Products -- 6. Data Availability and Data Generation Concepts -- 7. Activities Encountered by European and Other International Authorities.

This book closes a current gap by providing the scientific basis for consumer exposure assessment in the context of regulatory risk assessment. Risk is defined as the likelihood of an event occurring and the severity of its effects. The margin between the dose that leads to toxic effects and the actual dose of a chemical is identified by estimating population exposure. The objective of this book is to provide an introduction into the scientific principles of consumer exposure assessment, and to describe the methods used to estimate doses of chemicals, the statistics applied and computer tools needed. This is presented through the backgrounds of the special fields in exposure analysis, such as exposure via food and by the use of consumer products, toys, clothing and other items. As a general concept, human exposure is also understood to include exposure via the environment and from the work setting. In this context, the specific features of consumer exposure are pointed out and put into the context of regulation, in particular food safety, chemicals safety (REACh) and consumer product safety. The book is structured into three parts: The first part deals with the general concepts of consumer exposure as part of the overall risk analysis framework of risk characterization, risk assessment and risk communication. It describes the three basic features of exposure assessment (i) the exposure scenario (ii) the exposure model and (iii) the exposure parameters, addressing external and internal exposure. Also, the statistical presentation of data to characterize populations, in connection with variability, uncertainty and quality of information and the presentation of exposure evaluation results is described. The second part deals with the specific issues of exposure assessment, exposure via food consumption, exposure from use of consumer products, household products, toys, cosmetic products, textiles, pesticides and others. This part also covers methods for acquisition of data for exposure estimations, including the relevant information from regulations needed to perform an accurate exposure assessment. The third part portrays a prospect for further needs in the development and improvement of consumer exposure assessment, as well as international activities and descriptions of the work of institutions that are involved in exposure assessment on the regulatory and scientific level. And conversely, it creates the rationale for the exposure assessment details necessary to satisfy regulatory needs such as derivation of upper limits and risk management issues.

ISBN: 9783319961484$q(electronic bk.)

Standard No.: 10.1007/978-3-319-96148-4doiSubjects--Topical Terms:

237657
Pharmaceutical technology.

LC Class. No.: RS380 / .P733 2019

Dewey Class. No.: 615.19

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245 0 4 $a The practice of consumer exposure assessment $h [electronic resource] / $c edited by Gerhard Heinemeyer, Matti Jantunen, Pertti Hakkinen.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2019.
300 $a xxxvi, 584 p. : $b ill. (some col.), digital ; $c 24 cm.
505 0 $a 1. General Introduction -- 2. Major Principles and Concepts of Risk Assessment -- 3. General Aspects of Exposure Evaluation -- 4. Exposure to Substances via Food Consumption -- 5. Exposure to Substances by use of Consumer Products -- 6. Data Availability and Data Generation Concepts -- 7. Activities Encountered by European and Other International Authorities.
520 $a This book closes a current gap by providing the scientific basis for consumer exposure assessment in the context of regulatory risk assessment. Risk is defined as the likelihood of an event occurring and the severity of its effects. The margin between the dose that leads to toxic effects and the actual dose of a chemical is identified by estimating population exposure. The objective of this book is to provide an introduction into the scientific principles of consumer exposure assessment, and to describe the methods used to estimate doses of chemicals, the statistics applied and computer tools needed. This is presented through the backgrounds of the special fields in exposure analysis, such as exposure via food and by the use of consumer products, toys, clothing and other items. As a general concept, human exposure is also understood to include exposure via the environment and from the work setting. In this context, the specific features of consumer exposure are pointed out and put into the context of regulation, in particular food safety, chemicals safety (REACh) and consumer product safety. The book is structured into three parts: The first part deals with the general concepts of consumer exposure as part of the overall risk analysis framework of risk characterization, risk assessment and risk communication. It describes the three basic features of exposure assessment (i) the exposure scenario (ii) the exposure model and (iii) the exposure parameters, addressing external and internal exposure. Also, the statistical presentation of data to characterize populations, in connection with variability, uncertainty and quality of information and the presentation of exposure evaluation results is described. The second part deals with the specific issues of exposure assessment, exposure via food consumption, exposure from use of consumer products, household products, toys, cosmetic products, textiles, pesticides and others. This part also covers methods for acquisition of data for exposure estimations, including the relevant information from regulations needed to perform an accurate exposure assessment. The third part portrays a prospect for further needs in the development and improvement of consumer exposure assessment, as well as international activities and descriptions of the work of institutions that are involved in exposure assessment on the regulatory and scientific level. And conversely, it creates the rationale for the exposure assessment details necessary to satisfy regulatory needs such as derivation of upper limits and risk management issues.
650 0 $a Pharmaceutical technology. $3 237657
650 0 $a Medicine, Industrial. $3 317703
650 0 $a Chemistry. $3 188628
650 1 4 $a Pharmaceutical Sciences/Technology. $3 338426
650 2 4 $a Occupational Medicine/Industrial Medicine. $3 278042
650 2 4 $a Safety in Chemistry, Dangerous Goods. $3 283758
700 1 $a Heinemeyer, Gerhard. $3 878094
700 1 $a Jantunen, Matti. $3 878095
700 1 $a Hakkinen, Pertti. $3 878096
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856 4 0 $u https://doi.org/10.1007/978-3-319-96148-4
950 $a Biomedical and Life Sciences (SpringerNature-11642)