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Basic epithelial ion transport princ...

Devor, Daniel C.

Basic epithelial ion transport principles and functionion channels and transporters of epithelia in health and disease.Vol. 1 /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Basic epithelial ion transport principles and functionedited by Kirk L. Hamilton, Daniel C. Devor.
Reminder of title:	ion channels and transporters of epithelia in health and disease.
other author:	Hamilton, Kirk L.
Published:	Cham :Springer International Publishing :2020.
Description:	xix, 563 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Ion channels.
Online resource:	https://doi.org/10.1007/978-3-030-52780-8
ISBN:	9783030527808$q(electronic bk.)

Basic epithelial ion transport principles and functionion channels and transporters of epithelia in health and disease.Vol. 1 /
Basic epithelial ion transport principles and functionion channels and transporters of epithelia in health and disease.Vol. 1 /[electronic resource] :edited by Kirk L. Hamilton, Daniel C. Devor. - Second edition. - Cham :Springer International Publishing :2020. - xix, 563 p. :ill., digital ;24 cm. - Physiology in health and disease,2625-252X. - Physiology in health and disease..

1. Techniques in Epithelial Transport -- 2. Understanding Transepithelial Current Measurements -- 3. Mathematical Modeling of Epithelial Ion Transport -- 4. Rationale of Epithelia Transport -- 5. Establishment of Epithelial Polarity -- 6. Molecular Mechanisms of Apical and Basolateral Sorting in Polarized Epithelial Cells -- 7. Membrane Protein Folding and Structure -- 8. Epithelial Ion Channel Folding and ER Associated Degradation (ERAD) -- 9. Fundamentals of Epithelial Cl- Transport -- 10. Fundamentals of Epithelial Na+ Absorption -- 11. Physiologic Influences of Transepithelial K+ Secretion -- 12. Volume Regulation in Epithelia -- 13. Fundamentals of Bicarbonate Secretion in Epithelia -- 14. Sexual Dimorphism of Epithelial Ion Channels -- 15. Non-coding RNA-Dependent Regulation of Channels/Transporters.

This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.

ISBN: 9783030527808$q(electronic bk.)

Standard No.: 10.1007/978-3-030-52780-8doiSubjects--Topical Terms:

195439
Ion channels.

LC Class. No.: QH603.I54

Dewey Class. No.: 611.0187

Basic epithelial ion transport principles and functionion channels and transporters of epithelia in health and disease.Vol. 1 /
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505 0 $a 1. Techniques in Epithelial Transport -- 2. Understanding Transepithelial Current Measurements -- 3. Mathematical Modeling of Epithelial Ion Transport -- 4. Rationale of Epithelia Transport -- 5. Establishment of Epithelial Polarity -- 6. Molecular Mechanisms of Apical and Basolateral Sorting in Polarized Epithelial Cells -- 7. Membrane Protein Folding and Structure -- 8. Epithelial Ion Channel Folding and ER Associated Degradation (ERAD) -- 9. Fundamentals of Epithelial Cl- Transport -- 10. Fundamentals of Epithelial Na+ Absorption -- 11. Physiologic Influences of Transepithelial K+ Secretion -- 12. Volume Regulation in Epithelia -- 13. Fundamentals of Bicarbonate Secretion in Epithelia -- 14. Sexual Dimorphism of Epithelial Ion Channels -- 15. Non-coding RNA-Dependent Regulation of Channels/Transporters.
520 $a This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.
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