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Advances in host-directed therapies ...

Gennaro, Maria Laura.

Advances in host-directed therapies against tuberculosis

Record Type:	Electronic resources : Monograph/item
Title/Author:	Advances in host-directed therapies against tuberculosisedited by Petros C. Karakousis, Richard Hafner, Maria Laura Gennaro.
other author:	Karakousis, Petros C.
Published:	Cham :Springer International Publishing :2021.
Description:	xiii, 332 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	TuberculosisImmunotherapy.
Online resource:	https://doi.org/10.1007/978-3-030-56905-1
ISBN:	9783030569051$q(electronic bk.)

Advances in host-directed therapies against tuberculosis
Advances in host-directed therapies against tuberculosis[electronic resource] /edited by Petros C. Karakousis, Richard Hafner, Maria Laura Gennaro. - Cham :Springer International Publishing :2021. - xiii, 332 p. :ill., digital ;24 cm.

This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT) The pathways/mechanisms investigated are either protective - thus calling for pathway/factor enhancing drugs - or maladaptive - thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.

ISBN: 9783030569051$q(electronic bk.)

Standard No.: 10.1007/978-3-030-56905-1doiSubjects--Topical Terms:

888961
Tuberculosis
--Immunotherapy.

LC Class. No.: RC311.3.C45

Dewey Class. No.: 616.995

Advances in host-directed therapies against tuberculosis
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245 0 0 $a Advances in host-directed therapies against tuberculosis $h [electronic resource] / $c edited by Petros C. Karakousis, Richard Hafner, Maria Laura Gennaro.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2021.
300 $a xiii, 332 p. : $b ill., digital ; $c 24 cm.
520 $a This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT) The pathways/mechanisms investigated are either protective - thus calling for pathway/factor enhancing drugs - or maladaptive - thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.
650 0 $a Tuberculosis $x Immunotherapy. $3 888961
650 0 $a Immunotherapy $x Methods. $3 888962
650 1 4 $a Immunology. $3 189152
650 2 4 $a Infectious Diseases. $3 274275
650 2 4 $a Pharmacotherapy. $3 615025
700 1 $a Karakousis, Petros C. $3 888958
700 1 $a Hafner, Richard. $3 888959
700 1 $a Gennaro, Maria Laura. $3 888960
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-3-030-56905-1
950 $a Biomedical and Life Sciences (SpringerNature-11642)