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Collagen biografts for tunable drug ...

Joshi, Rucha.

Collagen biografts for tunable drug delivery

Record Type:	Electronic resources : Monograph/item
Title/Author:	Collagen biografts for tunable drug deliveryby Rucha Joshi.
Author:	Joshi, Rucha.
Published:	Cham :Springer International Publishing :2021.
Description:	xii, 107 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Biomedical materialsTherapeutic use.
Online resource:	https://doi.org/10.1007/978-3-030-63817-7
ISBN:	9783030638177$q(electronic bk.)

Collagen biografts for tunable drug delivery
Joshi, Rucha.

Collagen biografts for tunable drug delivery[electronic resource] /by Rucha Joshi. - Cham :Springer International Publishing :2021. - xii, 107 p. :ill., digital ;24 cm. - SpringerBriefs in applied sciences and technology,2191-530X. - SpringerBriefs in applied sciences and technology..

Introduction -- Creating Tunable Collagen Matrices - An Approach Inspired by In-Vivo Collagen Synthesis and Self-Assembly -- Application of Collagen Fibril Biografts for Enhancing Local Vascularization in an In-Vivo Chick Chorioallantoic Membrane (CAM) Model -- Appendix A: Type I Collagen Based Drug Delivery Formats -- Appendix B: State-of-the-Art Methods of Tuning Collagen Based Molecular Release.

This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.

ISBN: 9783030638177$q(electronic bk.)

Standard No.: 10.1007/978-3-030-63817-7doiSubjects--Topical Terms:

890252
Biomedical materials
--Therapeutic use.

LC Class. No.: QP552.C6 / J674 2021

Dewey Class. No.: 610.284

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505 0 $a Introduction -- Creating Tunable Collagen Matrices - An Approach Inspired by In-Vivo Collagen Synthesis and Self-Assembly -- Application of Collagen Fibril Biografts for Enhancing Local Vascularization in an In-Vivo Chick Chorioallantoic Membrane (CAM) Model -- Appendix A: Type I Collagen Based Drug Delivery Formats -- Appendix B: State-of-the-Art Methods of Tuning Collagen Based Molecular Release.
520 $a This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.
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