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Hematologic malignanciescase studies...

Bhargava, Manorama.

Hematologic malignanciescase studies in cytogenetic and molecular genetics /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Hematologic malignanciesby Manorama Bhargava.
Reminder of title:	case studies in cytogenetic and molecular genetics /
Author:	Bhargava, Manorama.
Published:	Singapore :Springer Singapore :2021.
Description:	xxvi, 246 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	LeukemiaCase studies.Genetic aspects
Online resource:	https://doi.org/10.1007/978-981-33-4799-1
ISBN:	9789813347991$q(electronic bk.)

Hematologic malignanciescase studies in cytogenetic and molecular genetics /
Bhargava, Manorama.

Hematologic malignanciescase studies in cytogenetic and molecular genetics /[electronic resource] :by Manorama Bhargava. - Singapore :Springer Singapore :2021. - xxvi, 246 p. :ill., digital ;24 cm.

Techniques in Cytogenetics -- Techniques in Molecular Haematology -- Part: I - Case Studies in Myeloid Malignancies -- Acute Myeloid Leukemia -- Myelodysplastic Syndrome -- Myelodysplastic Syndromes - Myeloproliferative Neoplasms -- Myeloproliferative Neoplasms -- Chronic Myeloid Leukemia -- Next Generation Sequencing for Diagnostics of Myeloid Malignancies for Routine Clinical Use: Pitfalls and Advantages -- Part: II - Case Studies in Lymphoid Malignancies -- Acute Lymphoblastic Leukemia -- Chronic Lymphocytic Leukemia and Non Hodgkin's Lymphoma -- Part: III - Case Studies in Multiple Myeloma -- Multiple Myeloma.

This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.

ISBN: 9789813347991$q(electronic bk.)

Standard No.: 10.1007/978-981-33-4799-1doiSubjects--Topical Terms:

895333
Leukemia
--Genetic aspects--Case studies.

LC Class. No.: RC643

Dewey Class. No.: 616.99419

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505 0 $a Techniques in Cytogenetics -- Techniques in Molecular Haematology -- Part: I - Case Studies in Myeloid Malignancies -- Acute Myeloid Leukemia -- Myelodysplastic Syndrome -- Myelodysplastic Syndromes - Myeloproliferative Neoplasms -- Myeloproliferative Neoplasms -- Chronic Myeloid Leukemia -- Next Generation Sequencing for Diagnostics of Myeloid Malignancies for Routine Clinical Use: Pitfalls and Advantages -- Part: II - Case Studies in Lymphoid Malignancies -- Acute Lymphoblastic Leukemia -- Chronic Lymphocytic Leukemia and Non Hodgkin's Lymphoma -- Part: III - Case Studies in Multiple Myeloma -- Multiple Myeloma.
520 $a This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.
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