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SARS-CoV-2 spike protein convergent ...

Focosi, Daniele.

SARS-CoV-2 spike protein convergent evolutionimpact of virus variants on efficacy of COVID-19 therapeutics and vaccines /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	SARS-CoV-2 spike protein convergent evolutionby Daniele Focosi.
其他題名:	impact of virus variants on efficacy of COVID-19 therapeutics and vaccines /
作者:	Focosi, Daniele.
出版者:	Cham :Springer International Publishing :2021.
面頁冊數:	xiii, 136 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	COVID-19 (Disease)
電子資源:	https://doi.org/10.1007/978-3-030-87324-0
ISBN:	9783030873240$q(electronic bk.)

SARS-CoV-2 spike protein convergent evolutionimpact of virus variants on efficacy of COVID-19 therapeutics and vaccines /
Focosi, Daniele.

SARS-CoV-2 spike protein convergent evolutionimpact of virus variants on efficacy of COVID-19 therapeutics and vaccines /[electronic resource] :by Daniele Focosi. - Cham :Springer International Publishing :2021. - xiii, 136 p. :ill., digital ;24 cm. - SpringerBriefs in microbiology,2191-5393. - SpringerBriefs in microbiology..

Chapter 1. Why the Spike protein is relevant for COVID19 therapeutics -- Chapter 2. SARS-CoV-2 variants -- Chapter 3. Conclusion.

This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

ISBN: 9783030873240$q(electronic bk.)

Standard No.: 10.1007/978-3-030-87324-0doiSubjects--Topical Terms:

877725
COVID-19 (Disease)

LC Class. No.: RA644.C67

Dewey Class. No.: 614.592414

National Library of Medicine Call No.: QW 168.5.C8

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