國立高雄大學圖資館 |

Language: English

Back

Mixed-mode chromatographyprinciples,...

SpringerLink (Online service)

Mixed-mode chromatographyprinciples, methods, and applications /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Mixed-mode chromatographyby Qian-Hong Wan.
Reminder of title:	principles, methods, and applications /
Author:	Wan, Qian-Hong.
Published:	Singapore :Springer Singapore :2021.
Description:	xiii, 482 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Chromatographic analysis.
Online resource:	https://doi.org/10.1007/978-981-16-5485-5
ISBN:	9789811654855$q(electronic bk.)

Mixed-mode chromatographyprinciples, methods, and applications /
Wan, Qian-Hong.

Mixed-mode chromatographyprinciples, methods, and applications /[electronic resource] :by Qian-Hong Wan. - Singapore :Springer Singapore :2021. - xiii, 482 p. :ill. (some col.), digital ;24 cm.

Chapter 1.Historical Perspectives -- Chapter 2.Theoretical Background -- Chapter 3.Modes of Chromatographic Separation -- Chapter 4.Chromatographic Matrices -- Chapter 5.Ligand Design -- Chapter 6.Retention Mechanisms -- Chapter 7.Stationary Phases -- Chapter 8.Mobile Phases and Elution -- Chapter 9.Method Development -- Chapter 10.Applications in Biopharmaceutical Processing.

The book is about the technology and application of Mixed-mode chromatography (MMC) Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology.

ISBN: 9789811654855$q(electronic bk.)

Standard No.: 10.1007/978-981-16-5485-5doiSubjects--Topical Terms:

193953
Chromatographic analysis.

LC Class. No.: QP519.9.C47 / W36 2021

Dewey Class. No.: 543.8

National Library of Medicine Call No.: QT 36.5

Mixed-mode chromatographyprinciples, methods, and applications /
LDR:02519nmm a2200337 a 4500 001 613735
003 DE-He213
005 20211123133303.0
006 m d
007 cr nn 008maaau
008 220627s2021 si s 0 eng d
020 $a 9789811654855$q(electronic bk.)
020 $a 9789811654848$q(paper)
024 7 $a 10.1007/978-981-16-5485-5 $2 doi
035 $a 978-981-16-5485-5
040 $a GP $c GP
041 0 $a eng
050 4 $a QP519.9.C47 $b W36 2021
060 4 $a QT 36.5
072 7 $a TDCW $2 bicssc
072 7 $a MED072000 $2 bisacsh
072 7 $a TDC $2 thema
082 0 4 $a 543.8 $2 23
090 $a QP519.9.C47 $b W244 2021
100 1 $a Wan, Qian-Hong. $3 911755
245 1 0 $a Mixed-mode chromatography $h [electronic resource] : $b principles, methods, and applications / $c by Qian-Hong Wan.
260 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2021.
300 $a xiii, 482 p. : $b ill. (some col.), digital ; $c 24 cm.
505 0 $a Chapter 1.Historical Perspectives -- Chapter 2.Theoretical Background -- Chapter 3.Modes of Chromatographic Separation -- Chapter 4.Chromatographic Matrices -- Chapter 5.Ligand Design -- Chapter 6.Retention Mechanisms -- Chapter 7.Stationary Phases -- Chapter 8.Mobile Phases and Elution -- Chapter 9.Method Development -- Chapter 10.Applications in Biopharmaceutical Processing.
520 $a The book is about the technology and application of Mixed-mode chromatography (MMC) Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology.
650 0 $a Chromatographic analysis. $3 193953
650 1 4 $a Pharmaceutical Sciences/Technology. $3 338426
650 2 4 $a Chromatography. $3 470270
650 2 4 $a Laboratory Medicine. $3 276727
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-981-16-5485-5
950 $a Biomedical and Life Sciences (SpringerNature-11642)