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Single molecule science :from super-...

Appasani, Krishnarao, (1959-)

Single molecule science :from super-resolution microscopy to DNA mapping and diagnostics /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Single molecule science :edited by Krishnarao Appasani, Raghu Kiran Appasani ; foreword by Manfred Auer.
Reminder of title:	from super-resolution microscopy to DNA mapping and diagnostics /
other author:	Appasani, Krishnarao,
Description:	1 online resource (xxii, 147 pages) :illustrations (some color)
Subject:	Molecular biologyTechnique.
Online resource:	https://doi.org/10.1017/9781108525909
ISBN:	9781108525909

Single molecule science :from super-resolution microscopy to DNA mapping and diagnostics /
Single molecule science :from super-resolution microscopy to DNA mapping and diagnostics /edited by Krishnarao Appasani, Raghu Kiran Appasani ; foreword by Manfred Auer. - 1 online resource (xxii, 147 pages) :illustrations (some color)

Includes bibliographical references and index.

Part I: Super-Resolution Microscopy and Molecular Imaging Techniques to Probe Biology -- 1. Introduction on Single-Molecule Science -- 2. One Molecule, Two Molecules, Red Molecules, Blue Molecules: Methods for Quantifying Localization Microscopy Data -- 3. Multiscale Fluorescence Imaging -- 4. Long-Read Single-Molecule Optical Maps -- Part II: Protein Folding, Structure, Confirmation, and Dynamics -- 5. Single-Molecule Mechanics of Protein Nanomachines -- 6. Posttranslational Protein Translocation through Membranes at the Single-Molecule Level -- Part III: Mapping DNA Molecules at the Single-Molecule Level -- 7. Observing Dynamic States of Single-Molecule DNA and Proteins Using Atomic Force Microscope -- 8. Atomic Force Microscopy and Detecting a DNA Biomarker of a Few Copies without Amplification -- Part IV: Single-Molecule Biology to Study Gene Expression -- 9. Single-Molecule Detection in the Study of Gene Expression

"Single Molecule Science (SMS) has emerged from developing, using and combining technologies such as super-resolution microscopy, atomic force microscopy, and optical and magnetic tweezers, alongside sophisticated computational and modelling techniques. This comprehensive, edited volume brings together authoritative overviews of these methods from a biological perspective, and highlights how they can be used to observe and track individual molecules and monitor molecular interactions in living cells. Pioneers in this fast-moving field cover topics such as single molecule optical maps, nanomachines, and protein folding and dynamics. A particular emphasis is also given to mapping DNA molecules for diagnostic purposes, and the study of gene expression. With numerous illustrations, this book reveals how SMS has presented us with a new way of understanding life processes. A must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, biological imaging, genomics and structural biology"--

ISBN: 9781108525909

Source: cam 2200421 i 4500

LCCN: 2020041019Subjects--Topical Terms:

189145
Molecular biology
--Technique.

LC Class. No.: QH506 / .S5456 2022

Dewey Class. No.: 572.8/2

Single molecule science :from super-resolution microscopy to DNA mapping and diagnostics /
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245 0 0 $a Single molecule science : $b from super-resolution microscopy to DNA mapping and diagnostics / $c edited by Krishnarao Appasani, Raghu Kiran Appasani ; foreword by Manfred Auer.
264 1 $a Cambridge, United Kingdom ; $a New York, NY : $b Cambridge University Press, $c 2022.
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300 $a 1 online resource (xxii, 147 pages) : $b illustrations (some color)
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504 $a Includes bibliographical references and index.
505 0 $a Part I: Super-Resolution Microscopy and Molecular Imaging Techniques to Probe Biology -- 1. Introduction on Single-Molecule Science -- 2. One Molecule, Two Molecules, Red Molecules, Blue Molecules: Methods for Quantifying Localization Microscopy Data -- 3. Multiscale Fluorescence Imaging -- 4. Long-Read Single-Molecule Optical Maps -- Part II: Protein Folding, Structure, Confirmation, and Dynamics -- 5. Single-Molecule Mechanics of Protein Nanomachines -- 6. Posttranslational Protein Translocation through Membranes at the Single-Molecule Level -- Part III: Mapping DNA Molecules at the Single-Molecule Level -- 7. Observing Dynamic States of Single-Molecule DNA and Proteins Using Atomic Force Microscope -- 8. Atomic Force Microscopy and Detecting a DNA Biomarker of a Few Copies without Amplification -- Part IV: Single-Molecule Biology to Study Gene Expression -- 9. Single-Molecule Detection in the Study of Gene Expression
520 $a "Single Molecule Science (SMS) has emerged from developing, using and combining technologies such as super-resolution microscopy, atomic force microscopy, and optical and magnetic tweezers, alongside sophisticated computational and modelling techniques. This comprehensive, edited volume brings together authoritative overviews of these methods from a biological perspective, and highlights how they can be used to observe and track individual molecules and monitor molecular interactions in living cells. Pioneers in this fast-moving field cover topics such as single molecule optical maps, nanomachines, and protein folding and dynamics. A particular emphasis is also given to mapping DNA molecules for diagnostic purposes, and the study of gene expression. With numerous illustrations, this book reveals how SMS has presented us with a new way of understanding life processes. A must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, biological imaging, genomics and structural biology"-- $c Provided by publisher
588 $a Description based on online resource; title from digital title page (viewed on May 14, 2022).
650 0 $a Molecular biology $x Technique. $3 189145
650 0 $a Gene mapping $x Technological innovations. $3 913972
650 0 $a Microscopy $x Technological innovations. $3 913973
650 0 $a Biophysics. $3 188608
650 6 $a Biologie moléculaire $x Technique. $3 914076
650 6 $a Cartes chromosomiques $x Innovations. $3 913974
650 6 $a Microscopie $x Innovations. $3 913975
650 6 $a Biophysique. $3 913976
650 7 $a Biophysics $v Handbooks, manuals, etc. $3 438913
650 7 $a Molecular biology $x Technique $v Handbooks, manuals, etc. $3 646864
700 1 $a Appasani, Krishnarao, $d 1959- $e editor. $3 913970
700 1 $a Appasani, Raghu K., $e editor. $3 913971
776 0 8 $i Print version: $t Single molecule science. $d Cambridge, UK ; New york, NY : Cambridge University Press, 2020 $z 9781108423366 $w (DLC) 2020041018
856 4 0 $3 Cambridge University Press $u https://doi.org/10.1017/9781108525909
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