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The microbiome in respiratory diseaseprinciples, tools and applications /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The microbiome in respiratory diseaseedited by Yvonne J. Huang, Stavros Garantziotis.
其他題名:	principles, tools and applications /
其他作者:	Huang, Yvonne J.
出版者:	Cham :Springer International Publishing :2022.
面頁冊數:	xi, 305 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Respiratory organsDiseases
電子資源:	https://doi.org/10.1007/978-3-030-87104-8
ISBN:	9783030871048$q(electronic bk.)

The microbiome in respiratory diseaseprinciples, tools and applications /
The microbiome in respiratory diseaseprinciples, tools and applications /[electronic resource] :edited by Yvonne J. Huang, Stavros Garantziotis. - Cham :Springer International Publishing :2022. - xi, 305 p. :ill., digital ;24 cm. - Respiratory medicine,2197-7380. - Respiratory medicine..

SECTION I: Principles and Tools of Respiratory Microbiome Investigation -- Conceptual Framework and Hypothesis Testing -- Study Design and Sampling Considerations -- Laboratory Platforms to Study the Microbiome -- Analysis and Reporting of Microbiome Data -- SECTION II: Applications in the Study of Specific Diseases -- Chronic Rhinosinusitis /Allergic Rhinitis -- Bronchiolitis, Viral Infection and Pediatric Asthma Risk -- Asthma Pheotype -- Cystic Fibrosis -- Bronchiectasis (non-CF) -- COPD -- Idiopathic Pulmonary Fibrosis -- Lung Transplantation and Immune Suppression -- The Future: Knowledge gaps and priorities.

This book comprehensively covers the microbiome in respiratory disease, from the initial research study to the disease-specific implications and related applications. Research on the respiratory microbiome is increasing in volume and scope. This reflects rapidly growing interest in the study of respiratory disease to understand how microbiota shape mechanisms of disease pathogenesis. The respiratory tract spans the nasal passages, sinus cavities, oropharynx, and the tracheobronchial tree of the lungs. In these compartments of the upper and lower respiratory tract, the microbiota have now been studied in the context of several chronic respiratory conditions. These include chronic sinusitis, allergic rhinitis, asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis and pulmonary fibrosis, to name a few. The potential impact of ecological interactions (i.e., between microbes and between microbiota and host) within and across respiratory compartments is increasingly recognized. The book is organized into two main sections. Part I, Principles and Tools, covers conceptual modeling of the respiratory microbiome, experimental methodology with a focus on a priori considerations in study design and sampling, laboratory and computational methods for analysis of respiratory microbiome data, and minimizing interpretive pitfalls. Part II, Applications, discusses the evidence from specific studies that have shed novel insights into the influence of respiratory microbiota on mechanisms or outcomes in specific diseases. Based on current best evidence, disease-specific chapters include chronic rhinosinusitis, asthma (pediatric and adult studies), chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), bronchiectasis not due to CF, idiopathic pulmonary fibrosis, and lung transplant. This is an ideal reference for forward-thinking practitioners with interest in novel developments in precision medicine applications in lung disease, as well as translational scientists in the field of microbiology, immunology and lung biology.

ISBN: 9783030871048$q(electronic bk.)

Standard No.: 10.1007/978-3-030-87104-8doiSubjects--Topical Terms:

920033
Respiratory organs
--Diseases

LC Class. No.: RC732 / .M53 2022

Dewey Class. No.: 616.20041

National Library of Medicine Call No.: WF 140

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505 0 $a SECTION I: Principles and Tools of Respiratory Microbiome Investigation -- Conceptual Framework and Hypothesis Testing -- Study Design and Sampling Considerations -- Laboratory Platforms to Study the Microbiome -- Analysis and Reporting of Microbiome Data -- SECTION II: Applications in the Study of Specific Diseases -- Chronic Rhinosinusitis /Allergic Rhinitis -- Bronchiolitis, Viral Infection and Pediatric Asthma Risk -- Asthma Pheotype -- Cystic Fibrosis -- Bronchiectasis (non-CF) -- COPD -- Idiopathic Pulmonary Fibrosis -- Lung Transplantation and Immune Suppression -- The Future: Knowledge gaps and priorities.
520 $a This book comprehensively covers the microbiome in respiratory disease, from the initial research study to the disease-specific implications and related applications. Research on the respiratory microbiome is increasing in volume and scope. This reflects rapidly growing interest in the study of respiratory disease to understand how microbiota shape mechanisms of disease pathogenesis. The respiratory tract spans the nasal passages, sinus cavities, oropharynx, and the tracheobronchial tree of the lungs. In these compartments of the upper and lower respiratory tract, the microbiota have now been studied in the context of several chronic respiratory conditions. These include chronic sinusitis, allergic rhinitis, asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis and pulmonary fibrosis, to name a few. The potential impact of ecological interactions (i.e., between microbes and between microbiota and host) within and across respiratory compartments is increasingly recognized. The book is organized into two main sections. Part I, Principles and Tools, covers conceptual modeling of the respiratory microbiome, experimental methodology with a focus on a priori considerations in study design and sampling, laboratory and computational methods for analysis of respiratory microbiome data, and minimizing interpretive pitfalls. Part II, Applications, discusses the evidence from specific studies that have shed novel insights into the influence of respiratory microbiota on mechanisms or outcomes in specific diseases. Based on current best evidence, disease-specific chapters include chronic rhinosinusitis, asthma (pediatric and adult studies), chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), bronchiectasis not due to CF, idiopathic pulmonary fibrosis, and lung transplant. This is an ideal reference for forward-thinking practitioners with interest in novel developments in precision medicine applications in lung disease, as well as translational scientists in the field of microbiology, immunology and lung biology.
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