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Handbook on nanobiomaterials for therapeutics and diagnostic applications

Record Type:	Electronic resources : Monograph/item
Title/Author:	Handbook on nanobiomaterials for therapeutics and diagnostic applicationsedited by Krishnan Anand ... [et al.].
other author:	Anand, Krishnan,
Published:	San Diego :Elsevier,2021.
Description:	1 online resource (612 p.).
Notes:	Includes index.
Subject:	Biomedical materials.
Online resource:	https://www.sciencedirect.com/science/book/9780128210130
ISBN:	9780128219140 (electronic bk.)

Handbook on nanobiomaterials for therapeutics and diagnostic applications
Handbook on nanobiomaterials for therapeutics and diagnostic applications[electronic resource] /edited by Krishnan Anand ... [et al.]. - San Diego :Elsevier,2021. - 1 online resource (612 p.).

Includes index.

Intro -- Handbook on Nanobiomaterials For Therapeutics and Diagnostic Applications -- Copyright -- Contents -- Contributors -- Chapter 1 Nanosomes for drug delivery -- 1.1 Introduction -- 1.2 Drug delivery system -- 1.3 Pharmacokinetics and pharmacodynamics -- 1.4 Types of nanosomes in drug delivery -- 1.4.1 Endosomes in drug delivery -- 1.4.2 Exosomes in drug delivery -- 1.4.3 Liposomes in drug delivery -- 1.4.4 siRNA-encapsulated nanosomes in drug delivery -- 1.4.4.1 Epidemiology -- 1.5 Nanosomes and gene therapy -- 1.6 Nanosome transportation mechanisms.

ISBN: 9780128219140 (electronic bk.)Subjects--Topical Terms:

193830
Biomedical materials.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: R857.M3

Dewey Class. No.: 610.28

Handbook on nanobiomaterials for therapeutics and diagnostic applications
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245 0 0 $a Handbook on nanobiomaterials for therapeutics and diagnostic applications $h [electronic resource] / $c edited by Krishnan Anand ... [et al.].
260 $a San Diego : $b Elsevier, $c 2021.
300 $a 1 online resource (612 p.).
500 $a Includes index.
505 0 $a Intro -- Handbook on Nanobiomaterials For Therapeutics and Diagnostic Applications -- Copyright -- Contents -- Contributors -- Chapter 1 Nanosomes for drug delivery -- 1.1 Introduction -- 1.2 Drug delivery system -- 1.3 Pharmacokinetics and pharmacodynamics -- 1.4 Types of nanosomes in drug delivery -- 1.4.1 Endosomes in drug delivery -- 1.4.2 Exosomes in drug delivery -- 1.4.3 Liposomes in drug delivery -- 1.4.4 siRNA-encapsulated nanosomes in drug delivery -- 1.4.4.1 Epidemiology -- 1.5 Nanosomes and gene therapy -- 1.6 Nanosome transportation mechanisms.
505 8 $a 1.7 Blockades of nanosome trafficking -- 1.8 Drug release -- 1.9 Conclusion -- References -- Chapter 2 Nanomaterials for bioimaging studies -- 2.1 Introduction -- 2.2 Dye-loaded fluorescent silica nanoparticles (SiNPs) in bioimaging -- 2.2.1 Properties of SiNPs -- 2.2.2 Synthesis of SiNPs -- 2.2.3 Bioimaging -- 2.2.3.1 Typical fluorescent dye-doped SiNPs -- 2.2.3.2 Near-infrared fluorescent dye-doped SiNPs -- 2.2.3.3 Two-photon fluorescent dye silica nanoparticles -- 2.3 Imaging, targeting, and drug delivery using multifunctional inorganic nanoparticles (MiNPs).
505 8 $a 2.4 Lanthanide-doped upconverting nanoparticles -- 2.4.1 The fundamental mechanism of UCNPs -- 2.4.2 Synthesis of UCNPs -- 2.4.3 UCNPs as image contrasting agents -- 2.5 Conclusions -- References -- Chapter 3 Exosome RNAs as biomarkers for cancer therapy -- 3.1 Introduction -- 3.2 Exosomes in cancer -- 3.3 Exosomes from body fluids -- 3.3.1 Resistance to cancer therapeutics -- 3.3.2 Nanodiagnostic exosomes by electrochemical biosensing -- 3.3.3 Characterization of salivary exosomes -- 3.4 Exosomes derived from tumor cells -- 3.4.1 Role of exosomes in metastasis of cancer cells.
505 8 $a 3.4.2 State of exosomes within the enlargement of cancer tissue amidst angiogenesis -- 3.5 Exosomes-Role in maintaining a strategic distance from an assault from immune cells -- 3.6 Potential benefits of exosomal RNAs in malignant growth diagnostics and treatment -- 3.6.1 Exosomal ncRNAs as malignancy indicative biomarkers -- 3.6.2 Uses of exosomal noncoding RNAs (ncRNAs) as cancer therapeutics -- 3.7 Conclusion -- References -- Chapter 4 Tumoral delivery of nanotherapeutics -- 4.1 Introduction -- 4.2 Therapeutics employed for tumor treatment -- 4.2.1 Chemotherapy -- 4.2.2 Genetic material.
505 8 $a 4.2.3 Photodynamic therapy (PDT) -- 4.2.4 Photothermal therapy (PTT) -- 4.2.5 Immunotherapy -- 4.2.6 Sonodynamic therapy -- 4.3 Barriers to tumoral delivery of nanotherapeutics -- 4.3.1 Barriers in the systemic circulation -- 4.3.2 Barriers in the tumor microenvironment -- 4.3.3 Barriers at cellular level -- 4.3.4 Heterogeneity in vascular density among different tumors -- 4.4 Potential of nanocarriers for tumoral delivery of therapeutics -- 4.4.1 Chemotherapy -- 4.4.2 Gene therapy -- 4.4.3 PDT -- 4.4.4 PTT -- 4.4.5 Combination therapy -- 4.4.6 Targeted therapy -- 4.4.6.1 Passive targeting. 4.4.6.2 Active targeting.
650 0 $a Biomedical materials. $3 193830
650 0 $a Nanostructured materials. $3 216041
650 0 $a Nanobiotechnology. $3 679667
655 4 $a Electronic books. $2 local. $3 214472
700 1 $a Anand, Krishnan, $e editor. $3 926589
856 4 0 $u https://www.sciencedirect.com/science/book/9780128210130