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High altitude sickness -- solutions from genomics, proteomics and antioxidant interventions

Record Type:	Electronic resources : Monograph/item
Title/Author:	High altitude sickness -- solutions from genomics, proteomics and antioxidant interventionsedited by Narendra Kumar Sharma, Aditya Arya.
other author:	Sharma, Narendra Kumar.
Published:	Singapore :Springer Nature Singapore :2022.
Description:	xi, 223 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Mountain sickness.
Online resource:	https://doi.org/10.1007/978-981-19-1008-1
ISBN:	9789811910081$q(electronic bk.)

High altitude sickness -- solutions from genomics, proteomics and antioxidant interventions
High altitude sickness -- solutions from genomics, proteomics and antioxidant interventions[electronic resource] /edited by Narendra Kumar Sharma, Aditya Arya. - Singapore :Springer Nature Singapore :2022. - xi, 223 p. :ill., digital ;24 cm.

1 Introduction to High Altitude and Hypoxia -- 2 High altitude sickness: environmental stressor and altered physiological response -- 3 High-Altitude Related Diseases: Milder Effects, HACE, HAPE, and Effect on Various Organ Systems -- 4 High altitude-induced Oxidative stress, Rheumatoid Arthritis and proteomic alteration -- 5 Oxidative Stress, ROS generation and Associated Molecular Alterations in High Altitude Hypoxia -- 6 Oxidative Stress, ROS generation and Associated Molecular Alterations in High Altitude Hypoxia -- 7 Current problems in diagnosis and treatment of high altitude sickness -- 8 Proteomics as a potential tool for biomarker discovery -- 9 Serum and Plasma Proteomics for High-Altitude Related Biomarker Discovery -- 10 Saliva Proteomics As Non-Invasive Application For Biomarker Studies -- 11 Role of genomics, proteomics and antioxidant interventions in preventing High Altitude Sickness -- 12 High Altitude Sickness And Antioxidant Interventions -- 13 Antioxidant therapy for high altitude sickness and Nano-medicine.

This book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and explores the potential of antioxidant therapy for this sickness. The first chapters introduce the associated pathophysiology and provide mechanistic insights into the enhanced generation of reactive oxygen and nitrogen species (RONS), which leads to an increase in oxidative damage to lipids, proteins, and DNA. The book then highlights the current problems relating to the diagnosis and treatment of altitude sickness and summarizes novel approaches for identifying potential biomarkers and therapeutics. Lastly, it explores the therapeutic efficacy of antioxidant agents.

ISBN: 9789811910081$q(electronic bk.)

Standard No.: 10.1007/978-981-19-1008-1doiSubjects--Topical Terms:

929070
Mountain sickness.

LC Class. No.: RC103.M63 / H54 2022

Dewey Class. No.: 616.9893

High altitude sickness -- solutions from genomics, proteomics and antioxidant interventions
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505 0 $a 1 Introduction to High Altitude and Hypoxia -- 2 High altitude sickness: environmental stressor and altered physiological response -- 3 High-Altitude Related Diseases: Milder Effects, HACE, HAPE, and Effect on Various Organ Systems -- 4 High altitude-induced Oxidative stress, Rheumatoid Arthritis and proteomic alteration -- 5 Oxidative Stress, ROS generation and Associated Molecular Alterations in High Altitude Hypoxia -- 6 Oxidative Stress, ROS generation and Associated Molecular Alterations in High Altitude Hypoxia -- 7 Current problems in diagnosis and treatment of high altitude sickness -- 8 Proteomics as a potential tool for biomarker discovery -- 9 Serum and Plasma Proteomics for High-Altitude Related Biomarker Discovery -- 10 Saliva Proteomics As Non-Invasive Application For Biomarker Studies -- 11 Role of genomics, proteomics and antioxidant interventions in preventing High Altitude Sickness -- 12 High Altitude Sickness And Antioxidant Interventions -- 13 Antioxidant therapy for high altitude sickness and Nano-medicine.
520 $a This book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and explores the potential of antioxidant therapy for this sickness. The first chapters introduce the associated pathophysiology and provide mechanistic insights into the enhanced generation of reactive oxygen and nitrogen species (RONS), which leads to an increase in oxidative damage to lipids, proteins, and DNA. The book then highlights the current problems relating to the diagnosis and treatment of altitude sickness and summarizes novel approaches for identifying potential biomarkers and therapeutics. Lastly, it explores the therapeutic efficacy of antioxidant agents.
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650 0 $a Anoxemia. $3 491892
650 1 4 $a Human Physiology. $3 274509
650 2 4 $a Life Sciences. $3 273679
650 2 4 $a Cell Biology. $3 274165
700 1 $a Sharma, Narendra Kumar. $3 929068
700 1 $a Arya, Aditya. $3 929069
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