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Discovery DMPK quick guideguide to data interpretation and integration /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Discovery DMPK quick guideby S. Cyrus Khojasteh ... [et al.].
其他題名:	guide to data interpretation and integration /
其他作者:	Khojasteh, Siamak Cyrus.
出版者:	Cham :Springer International Publishing :2022.
面頁冊數:	xxi, 228 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Drug development.
電子資源:	https://doi.org/10.1007/978-3-031-10691-0
ISBN:	9783031106910$q(electronic bk.)

Discovery DMPK quick guideguide to data interpretation and integration /
Discovery DMPK quick guideguide to data interpretation and integration /[electronic resource] :by S. Cyrus Khojasteh ... [et al.]. - Cham :Springer International Publishing :2022. - xxi, 228 p. :ill., digital ;24 cm.

Goals for DMPK during drug optimizations -- Drug Properties -- DMPK in lead optimization -- Candidate tranlational characterization -- Q&A of DMPK issues and tools for drug discovery -- ADME assays -- Regulatory documents for IND to Support FIH -- Appendix: Chemical nomenclature.

This book is intended for a broad readership, in particular, those working or interested in drug discovery coming from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics, and toxicology. It provides, for the first time, a completely integrated look at multiple aspects of ADME sciences (absorption, distribution, metabolism, and excretion) in a summary format that is clear, concise, and self-explanatory. DMPK in Drug Discovery - Guide to Data Interpretation and integration leverages the prior knowledge from the first book that covers the basics of each concept (Drug Metabolism and Pharmacokinetics Quick Guide) This reference book is meant to be used day to day and provides many useful tables (used for data interpretation), figures, and case studies that can facilitate drug discovery. The case studies are intended to be short and relevant to the topic discussed and present another dimension to the discussions.

ISBN: 9783031106910$q(electronic bk.)

Standard No.: 10.1007/978-3-031-10691-0doiSubjects--Topical Terms:

190608
Drug development.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

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520 $a This book is intended for a broad readership, in particular, those working or interested in drug discovery coming from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics, and toxicology. It provides, for the first time, a completely integrated look at multiple aspects of ADME sciences (absorption, distribution, metabolism, and excretion) in a summary format that is clear, concise, and self-explanatory. DMPK in Drug Discovery - Guide to Data Interpretation and integration leverages the prior knowledge from the first book that covers the basics of each concept (Drug Metabolism and Pharmacokinetics Quick Guide) This reference book is meant to be used day to day and provides many useful tables (used for data interpretation), figures, and case studies that can facilitate drug discovery. The case studies are intended to be short and relevant to the topic discussed and present another dimension to the discussions.
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