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Genome editing in drug discovery

Record Type:	Electronic resources : Monograph/item
Title/Author:	Genome editing in drug discoveryMarcello Maresca, Sumit Deswal.
other author:	Maresca, Marcello.
Published:	Hoboken, NJ :Wiley,2022.
Description:	1 online resource (x, 342 p.) :ill. (chiefly col.)
Subject:	Drug development.
Online resource:	https://onlinelibrary.wiley.com/doi/book/10.1002/9781119671404
ISBN:	9781119671404$q(electronic bk.)

Genome editing in drug discovery
Genome editing in drug discovery[electronic resource] /Marcello Maresca, Sumit Deswal. - Hoboken, NJ :Wiley,2022. - 1 online resource (x, 342 p.) :ill. (chiefly col.)

Includes bibliographical references and index.

"CRISPR-Cas has revolutionized genome editing by allowing researchers to remove, alter, or add sections of the DNA sequence. By performing large scale functional genomics screens with CRISPR-Cas, scientists can identify and validate drug targets at a much faster rate. Genome editing is now part of almost every step in the drug discovery pipeline, from target identification and its validation to mechanistic studies in relevant disease models to therapeutic genome editing and disease diagnosis. Genome Editing in Drug Discovery offers comprehensive coverage of the revolution CRISPR-Cas has brought to genome editing and its impact on drug discovery. Ideal for academics, researchers, and professionals in the pharmaceutical industry; this book helps readers create better disease models, assess the safety and efficacy of drugs, discover new targets, and develop next-generation diagnostics for disease-related genes. This book provides a historical prospective on genome editing, discusses the general approaches used to make disease models, and offers practical suggestions as the technology advances"--

ISBN: 9781119671404$q(electronic bk.)

Standard No.: 10.1002/9781119671404doiSubjects--Topical Terms:

190608
Drug development.

LC Class. No.: RM301.25 / .G46 2022

Dewey Class. No.: 615.1/9

Genome editing in drug discovery
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024 7 $a 10.1002/9781119671404 $2 doi
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050 0 4 $a RM301.25 $b .G46 2022
082 0 0 $a 615.1/9 $2 23
245 0 0 $a Genome editing in drug discovery $h [electronic resource] / $c Marcello Maresca, Sumit Deswal.
260 $a Hoboken, NJ : $b Wiley, $c 2022.
300 $a 1 online resource (x, 342 p.) : $b ill. (chiefly col.)
504 $a Includes bibliographical references and index.
520 $a "CRISPR-Cas has revolutionized genome editing by allowing researchers to remove, alter, or add sections of the DNA sequence. By performing large scale functional genomics screens with CRISPR-Cas, scientists can identify and validate drug targets at a much faster rate. Genome editing is now part of almost every step in the drug discovery pipeline, from target identification and its validation to mechanistic studies in relevant disease models to therapeutic genome editing and disease diagnosis. Genome Editing in Drug Discovery offers comprehensive coverage of the revolution CRISPR-Cas has brought to genome editing and its impact on drug discovery. Ideal for academics, researchers, and professionals in the pharmaceutical industry; this book helps readers create better disease models, assess the safety and efficacy of drugs, discover new targets, and develop next-generation diagnostics for disease-related genes. This book provides a historical prospective on genome editing, discusses the general approaches used to make disease models, and offers practical suggestions as the technology advances"-- $c Provided by publisher.
588 $a Description based on print version record.
650 0 $a Drug development. $3 190608
650 0 $a Genetic engineering. $3 189009
700 1 $a Maresca, Marcello. $3 960537
700 1 $a Deswal, Sumit. $3 960538
856 4 0 $u https://onlinelibrary.wiley.com/doi/book/10.1002/9781119671404