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Ferroptosis in health and disease

Record Type:	Electronic resources : Monograph/item
Title/Author:	Ferroptosis in health and diseaseedited by Daolin Tang.
other author:	Tang, Daolin.
Published:	Cham :Springer International Publishing :2023.
Description:	viii, 490 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Cell death.
Online resource:	https://doi.org/10.1007/978-3-031-39171-2
ISBN:	9783031391712$q(electronic bk.)

Ferroptosis in health and disease
Ferroptosis in health and disease[electronic resource] /edited by Daolin Tang. - Second edition. - Cham :Springer International Publishing :2023. - viii, 490 p. :ill., digital ;24 cm.

Chapter 1. Lipid Metabolism and Homeostasis in Ferroptosis -- Chapter 2. Iron Metabolism and Ferroptosis -- Chapter 3. Targeting Epigenetic Regulation of Ferroptosis in Cancer Therapy -- Chapter 4. The Role of Autophagy in Ferroptosis -- Chapter 5. Heat Shock Proteins and HSF1 in Ferroptosis -- Chapter 6. The Ongoing Search for a Biomarker of Ferroptosis -- Chapter 7. p53 and Ferroptosis -- Chapter 8. Ferroptosis in Cardiovascular Disease -- Chapter 9. Understanding Ferroptosis from a Free Radical Perspective -- Chapter 10. The NRF2-anti-ferroptosis Axis in Health and Disease -- Chapter 11. Epigenetic Modification in Ferroptosis -- Chapter 12. Organelle-specific Mechanisms of Ferroptosis -- Chapter 13. Ferroptosis: A Promising Therapeutic Target for Cardiovascular Diseases -- Chapter 14. Ferroptosis in Central Nervous System Hypoxia-Ischemia -- Chapter 15. Involvement of Ferroptosis in Lupus Nephritis -- Chapter 16. Ferroptosis and Infectious Diseases -- Chapter 17. Selenium Metabolic Pathway in Ferroptotic Cell Death -- Chapter 18. Epigenetic and Post-Translational Regulation of Ferroptosis -- Chapter 19. Phospholipid Peroxidation in Health and Disease -- Chapter 20 -- PKCβII-ACSL4 Axis Triggers Ferroptosis and Its Potential Implication in Ferroptosis-Related Diseases -- Chapter 21. Cancer Treatment with Ferroptosis by a Combination of Iron Nanoparticles and Gene Therapy -- Chapter 22. Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimer's Disease.

This updated and expanded volume gives new insights on ferroptosis - an iron-dependent form of non-apoptotic cell death. The collection of chapters discusses the two major pathways through which ferroptosis can occur: the extrinsic or transporter-dependent pathway and the intrinsic or enzyme-regulated pathway. Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2. This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases.

ISBN: 9783031391712$q(electronic bk.)

Standard No.: 10.1007/978-3-031-39171-2doiSubjects--Topical Terms:

193735
Cell death.

LC Class. No.: QH671 / .F477 2023

Dewey Class. No.: 571.936

Ferroptosis in health and disease
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245 0 0 $a Ferroptosis in health and disease $h [electronic resource] / $c edited by Daolin Tang.
250 $a Second edition.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2023.
300 $a viii, 490 p. : $b ill., digital ; $c 24 cm.
505 0 $a Chapter 1. Lipid Metabolism and Homeostasis in Ferroptosis -- Chapter 2. Iron Metabolism and Ferroptosis -- Chapter 3. Targeting Epigenetic Regulation of Ferroptosis in Cancer Therapy -- Chapter 4. The Role of Autophagy in Ferroptosis -- Chapter 5. Heat Shock Proteins and HSF1 in Ferroptosis -- Chapter 6. The Ongoing Search for a Biomarker of Ferroptosis -- Chapter 7. p53 and Ferroptosis -- Chapter 8. Ferroptosis in Cardiovascular Disease -- Chapter 9. Understanding Ferroptosis from a Free Radical Perspective -- Chapter 10. The NRF2-anti-ferroptosis Axis in Health and Disease -- Chapter 11. Epigenetic Modification in Ferroptosis -- Chapter 12. Organelle-specific Mechanisms of Ferroptosis -- Chapter 13. Ferroptosis: A Promising Therapeutic Target for Cardiovascular Diseases -- Chapter 14. Ferroptosis in Central Nervous System Hypoxia-Ischemia -- Chapter 15. Involvement of Ferroptosis in Lupus Nephritis -- Chapter 16. Ferroptosis and Infectious Diseases -- Chapter 17. Selenium Metabolic Pathway in Ferroptotic Cell Death -- Chapter 18. Epigenetic and Post-Translational Regulation of Ferroptosis -- Chapter 19. Phospholipid Peroxidation in Health and Disease -- Chapter 20 -- PKCβII-ACSL4 Axis Triggers Ferroptosis and Its Potential Implication in Ferroptosis-Related Diseases -- Chapter 21. Cancer Treatment with Ferroptosis by a Combination of Iron Nanoparticles and Gene Therapy -- Chapter 22. Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimer's Disease.
520 $a This updated and expanded volume gives new insights on ferroptosis - an iron-dependent form of non-apoptotic cell death. The collection of chapters discusses the two major pathways through which ferroptosis can occur: the extrinsic or transporter-dependent pathway and the intrinsic or enzyme-regulated pathway. Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2. This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases.
650 0 $a Cell death. $3 193735
650 1 4 $a Cell Biology. $3 274165
650 2 4 $a Cell Death. $3 667149
650 2 4 $a Human Physiology. $3 274509
650 2 4 $a Protein Biochemistry. $3 933213
650 2 4 $a Cellular Stress. $3 911856
700 1 $a Tang, Daolin. $3 853414
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-3-031-39171-2
950 $a Medicine (SpringerNature-11650)