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Updates on Clostridioides difficile in Europe

Record Type:	Electronic resources : Monograph/item
Title/Author:	Updates on Clostridioides difficile in Europeedited by Paola Mastrantonio, Maja Rupnik.
other author:	Mastrantonio, Paola.
Published:	Cham :Springer International Publishing :2024.
Description:	x, 362 p. :ill. (chiefly col.), digital ;24 cm.
Notes:	"This is a second edition of volume 8 in this series."
Contained By:	Springer Nature eBook
Subject:	Clostridium difficile.
Online resource:	https://doi.org/10.1007/978-3-031-42108-2
ISBN:	9783031421082$q(electronic bk.)

Updates on Clostridioides difficile in Europe
Updates on Clostridioides difficile in Europe[electronic resource] /edited by Paola Mastrantonio, Maja Rupnik. - Second edition. - Cham :Springer International Publishing :2024. - x, 362 p. :ill. (chiefly col.), digital ;24 cm. - Advances in experimental medicine and biology ;v. 1435. - Advances in experimental medicine and biology ;946..

"This is a second edition of volume 8 in this series."

Economic burden of Clostridioides difficile infection in European countries -- The need for European surveillance of CDI -- Diagnostic guidance for C. difficile infections -- European practice for CDI treatment -- Faecal microbiota transplantation as emerging treatment in European countries 2.0 -- Probiotics for prevention and treatment of Clostridioides difficile infection -- Immunization strategies against Clostridioides difficile -- Ribotypes and new virulent strains across Europe -- Antibiotic resistances of Clostridioides difficile -- Comparative genomics of Clostridioides difficile -- An updated view on the cellular uptake and mode-of-action of Clostridioides difficile toxins -- Clostridioides difficile biofilm -- Clostridioides difficile sporulation -- Membrane vesicles of C.difficile and other Clostridial species -- Non-human C.difficile reservoirs and sources: animals,food, environment -- The ESCMID Study Group for Clostridioides difficile : history, role and perspectives.

This fully updated second edition outlines the currently available clinical, epidemiological and experimental data on Clostridioides difficile infections(CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are taken into consideration for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. New topics included sporulation and membrane vesicles in C. difficile. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.

ISBN: 9783031421082$q(electronic bk.)

Standard No.: 10.1007/978-3-031-42108-2doiSubjects--Topical Terms:

805223
Clostridium difficile.

LC Class. No.: QR201.C54

Dewey Class. No.: 616.931

Updates on Clostridioides difficile in Europe
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245 0 0 $a Updates on Clostridioides difficile in Europe $h [electronic resource] / $c edited by Paola Mastrantonio, Maja Rupnik.
250 $a Second edition.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2024.
300 $a x, 362 p. : $b ill. (chiefly col.), digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology ; $v v. 1435
500 $a "This is a second edition of volume 8 in this series."
505 0 $a Economic burden of Clostridioides difficile infection in European countries -- The need for European surveillance of CDI -- Diagnostic guidance for C. difficile infections -- European practice for CDI treatment -- Faecal microbiota transplantation as emerging treatment in European countries 2.0 -- Probiotics for prevention and treatment of Clostridioides difficile infection -- Immunization strategies against Clostridioides difficile -- Ribotypes and new virulent strains across Europe -- Antibiotic resistances of Clostridioides difficile -- Comparative genomics of Clostridioides difficile -- An updated view on the cellular uptake and mode-of-action of Clostridioides difficile toxins -- Clostridioides difficile biofilm -- Clostridioides difficile sporulation -- Membrane vesicles of C.difficile and other Clostridial species -- Non-human C.difficile reservoirs and sources: animals,food, environment -- The ESCMID Study Group for Clostridioides difficile : history, role and perspectives.
520 $a This fully updated second edition outlines the currently available clinical, epidemiological and experimental data on Clostridioides difficile infections(CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are taken into consideration for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. New topics included sporulation and membrane vesicles in C. difficile. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.
650 0 $a Clostridium difficile. $3 805223
650 0 $a Clostridium diseases $z Europe. $3 971630
650 0 $a Medical microbiology. $3 189151
650 2 4 $a Diseases. $3 276053
650 2 4 $a Microbiology. $3 192943
700 1 $a Mastrantonio, Paola. $3 805221
700 1 $a Rupnik, Maja. $3 805222
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
830 0 $a Advances in experimental medicine and biology ; $v 946. $3 557559
856 4 0 $u https://doi.org/10.1007/978-3-031-42108-2
950 $a Biomedical and Life Sciences (SpringerNature-11642)