國立高雄大學圖資館 |

Language: English

Back

A guide to sample size for animal-based studies

Record Type:	Electronic resources : Monograph/item
Title/Author:	A guide to sample size for animal-based studiesPenny S. Reynolds.
Author:	Reynolds, Penny S.
Published:	Hoboken, NJ :Wiley-Blackwell,2024.
Description:	1 online resource (280 p.) :ill. (some col.)
Subject:	Animal experimentationMethods.
Online resource:	https://onlinelibrary.wiley.com/doi/book/10.1002/9781119800002
ISBN:	9781119800002$q(electronic bk.)

A guide to sample size for animal-based studies
Reynolds, Penny S.

A guide to sample size for animal-based studies[electronic resource] /Penny S. Reynolds. - 1st ed. - Hoboken, NJ :Wiley-Blackwell,2024. - 1 online resource (280 p.) :ill. (some col.)

Includes bibliographical references and index.

"How large a sample size do I need for my study"? Although one of the most commonly-asked questions in statistics, the importance of proper sample size estimation seems to be overlooked by many preclinical researchers. Over the past two decades, numerous reviews of the published literature indicate many studies are too small to answer the research question and results are too unreliable to be trusted. Few published studies present adequate justification of their chosen sample sizes, or even report the total number of animals used. On the other hand, it is not unusual for protocols (usually those involving mouse models) to request preposterous numbers of animals, sometimes in the tens or even hundreds of thousands, "because this is an exploratory study, so it is unknown how many animals we will require."--

ISBN: 9781119800002$q(electronic bk.)Subjects--Topical Terms:

976709
Animal experimentation
--Methods.

LC Class. No.: R853.A53 / R49 2024

Dewey Class. No.: 616.02/7

National Library of Medicine Call No.: W 20.55.A5

A guide to sample size for animal-based studies
LDR:01975cmm a2200337 a 4500 001 664085
003 OCoLC
005 20240923072503.0
006 m o d
007 cr cnu---unuuu
008 241219s2024 njua ob 001 0 eng
020 $a 9781119800002$q(electronic bk.)
020 $a 1119800005$q(electronic bk.)
020 $a 9781119799993$q(electronic bk.)
020 $a 1119799996$q(electronic bk.)
020 $a 9781119799986$q(electronic bk.)
020 $a 1119799988$q(electronic bk.)
020 $z 9781119799979$q(paperback)
035 $a 1394905924
040 $a DLC $b eng $c DLC $d YDX $d DG1
041 0 $a eng
050 0 4 $a R853.A53 $b R49 2024
060 0 0 $a W 20.55.A5
082 0 0 $a 616.02/7 $2 23
100 1 $a Reynolds, Penny S. $3 976708
245 1 2 $a A guide to sample size for animal-based studies $h [electronic resource] / $c Penny S. Reynolds.
250 $a 1st ed.
260 $a Hoboken, NJ : $b Wiley-Blackwell, $c 2024.
300 $a 1 online resource (280 p.) : $b ill. (some col.)
504 $a Includes bibliographical references and index.
520 $a "How large a sample size do I need for my study"? Although one of the most commonly-asked questions in statistics, the importance of proper sample size estimation seems to be overlooked by many preclinical researchers. Over the past two decades, numerous reviews of the published literature indicate many studies are too small to answer the research question and results are too unreliable to be trusted. Few published studies present adequate justification of their chosen sample sizes, or even report the total number of animals used. On the other hand, it is not unusual for protocols (usually those involving mouse models) to request preposterous numbers of animals, sometimes in the tens or even hundreds of thousands, "because this is an exploratory study, so it is unknown how many animals we will require."-- $c Provided by publisher
588 $a Description based on print version record.
650 0 $a Animal experimentation $x Methods. $3 976709
650 0 $a Research $x Methodology. $3 182554
650 1 2 $a Animal Experimentation. $3 271279
650 2 2 $a Sample Size. $3 240258
856 4 0 $u https://onlinelibrary.wiley.com/doi/book/10.1002/9781119800002