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Activation and detoxification enzymesfunctions and implications /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Activation and detoxification enzymesby Chang-Hwei Chen.
其他題名:	functions and implications /
作者:	Chen, Chang-Hwei.
出版者:	Cham :Springer Nature Switzerland :2024.
面頁冊數:	xxi, 251 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Enzymes.
電子資源:	https://doi.org/10.1007/978-3-031-55287-8
ISBN:	9783031552878$q(electronic bk.)

Activation and detoxification enzymesfunctions and implications /
Chen, Chang-Hwei.

Activation and detoxification enzymesfunctions and implications /[electronic resource] :by Chang-Hwei Chen. - Second edition. - Cham :Springer Nature Switzerland :2024. - xxi, 251 p. :ill., digital ;24 cm.

Overview -- Foreign Compounds: Foods, Drugs, Chemicals and Life Styles -- Transport and Excretion of Foreign Compounds -- Metabolic Conversion of Foreign Compounds -- Phase I Activation Enzymes -- Phase II Detoxification Enzymes -- Catalytic Reactions of Activation Enzymes -- Catalytic Reactions of Detoxification Enzymes -- Reactive Intermediates and their Interactions -- Metabolite - Associated Cell Toxicities -- Oxidative Stress and Electrophilic Stress -- Metabolic Enzymes: Polymorphism and Species Differences -- Defense Against Oxidative Stress: Nrf2-ARE Pathway -- Inducibility of Metabolic Enzymes -- Inducers of Metabolic Enzymes -- Diversified Classes of Enzyme Modulators -- Metabolite - Mediated Disease Conditions -- Metabolic Enzyme Induction for Health Benefits -- Diet Effects on Metabolic Enzymes.

This book discusses the many advances in the understanding of the functions and implications of activation and detoxification enzymes. This organized, concise overview will meet the needs of those who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology, and chemistry. The book will also be valuable to advanced researchers. The book discusses subjects associated with foreign-compound-metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, activation and detoxification enzymes, metabolic enzyme catalytic properties, reactive metabolic intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary-related enzyme modulators, and structural characteristics of enzyme inducers. This new edition is updated throughout and features completely new chapters on Oxidative and Electrophilic Stresses, Metabolite- Mediated Disease Conditions, and Defense Mechanism: Nrf2-ARE Pathway.

ISBN: 9783031552878$q(electronic bk.)

Standard No.: 10.1007/978-3-031-55287-8doiSubjects--Topical Terms:

193013
Enzymes.

LC Class. No.: QP601

Dewey Class. No.: 572.7

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520 $a This book discusses the many advances in the understanding of the functions and implications of activation and detoxification enzymes. This organized, concise overview will meet the needs of those who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology, and chemistry. The book will also be valuable to advanced researchers. The book discusses subjects associated with foreign-compound-metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, activation and detoxification enzymes, metabolic enzyme catalytic properties, reactive metabolic intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary-related enzyme modulators, and structural characteristics of enzyme inducers. This new edition is updated throughout and features completely new chapters on Oxidative and Electrophilic Stresses, Metabolite- Mediated Disease Conditions, and Defense Mechanism: Nrf2-ARE Pathway.
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