國立高雄大學圖資館 |

Language: English

Back

Role of autophagy and reactive oxygen species in cancer treatmentprinciples and current strategies /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Role of autophagy and reactive oxygen species in cancer treatmentedited by Neeraj Mishra, Ravinder Kumar Kaundal.
Reminder of title:	principles and current strategies /
other author:	Mishra, Neeraj.
Published:	Cham :Springer Nature Switzerland :2024.
Description:	viii, 372 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	CancerMolecular aspects.
Online resource:	https://doi.org/10.1007/978-3-031-66421-2
ISBN:	9783031664212$q(electronic bk.)

Role of autophagy and reactive oxygen species in cancer treatmentprinciples and current strategies /
Role of autophagy and reactive oxygen species in cancer treatmentprinciples and current strategies /[electronic resource] :edited by Neeraj Mishra, Ravinder Kumar Kaundal. - Cham :Springer Nature Switzerland :2024. - viii, 372 p. :ill. (some col.), digital ;24 cm. - Cancer drug discovery and development,2196-9914. - Cancer drug discovery and development..

Preface -- Autophagy and Reactive Oxygen Species in Cancer: An Introduction -- Reactive Oxygen Species (ROS) and Cancer -- Unveiling Therapeutic Targets: Targeting Mitochondrial ROS for Anticancer Therapy -- Molecular Mechanisms of Autophagy Regulation in Cancer -- Autophagy and multi-drug resistance in cancer -- Interplay between Autophagy and Reactive Oxygen Species (ROS) -- Autophagy, Reactive Oxygen Species and Tumorigenesis -- Role of Autophagy and Oxidative Stress in Cancer Metastasis -- Autophagy-targeted Nanoparticles for the Treatment of Cancer -- Autophagy: A Critical Link between Immune Response and Cancer Progression -- Interplay between Autophagy and Apoptosis in Cancer: Mechanisms and Therapeutic Implications -- Unraveling the Nexus: Mitochondrial Oxidative Stress, Tumour Microenvironment, and Escape from Immune Surveillance -- Current Strategies for Targeting Autophagy and ROS for Cancer Treatment -- Exploring the Potential of Dietary Phytochemicals in Cancer Therapeutics: Modulating Apoptosis and Autophagy -- Clinical Trials and Future Prospects of Autophagy and ROS in Cancer -- Index.

Autophagy is a catabolic process that eliminates damaged and faulty cellular components via lysosomes. It responds to adverse circumstances like nutritional deficiency, hypoxia, and oxidative damage. Reactive oxygen species (ROS) cause oxidative stress, which is a multidimensional chemical that drives various pathophysiological diseases, including cancer. In addition, the autophagy process has a double role, first preventing tumour formation, but later fostering tumour progression. A growing body of research suggests that autophagy and ROS have a complex interplay in which they can either prevent cancer growth or enhance disease genesis. While a combination of autophagy inhibitor and cytotoxic medicines is now being used in cancer treatment, investigating the potential of autophagy inhibitors for overcoming resistance to different anticancer medications and how this relates to the control of cancer micro environmental stressors raises several questions. Autophagy's dual functions as a safeguarding and cytotoxic process have drawn attention to its significance in the development of cancer.

ISBN: 9783031664212$q(electronic bk.)

Standard No.: 10.1007/978-3-031-66421-2doiSubjects--Topical Terms:

221221
Cancer
--Molecular aspects.

LC Class. No.: RC268.4

Dewey Class. No.: 616.9940421

Role of autophagy and reactive oxygen species in cancer treatmentprinciples and current strategies /
LDR:03396nmm a22003495a 4500 001 667514
003 DE-He213
005 20240901130244.0
006 m d
007 cr nn 008maaau
008 250107s2024 sz s 0 eng d
020 $a 9783031664212$q(electronic bk.)
020 $a 9783031664205$q(paper)
024 7 $a 10.1007/978-3-031-66421-2 $2 doi
035 $a 978-3-031-66421-2
040 $a GP $c GP
041 0 $a eng
050 4 $a RC268.4
072 7 $a PSF $2 bicssc
072 7 $a SCI017000 $2 bisacsh
072 7 $a PSF $2 thema
082 0 4 $a 616.9940421 $2 23
090 $a RC268.4 $b .R745 2024
245 0 0 $a Role of autophagy and reactive oxygen species in cancer treatment $h [electronic resource] : $b principles and current strategies / $c edited by Neeraj Mishra, Ravinder Kumar Kaundal.
260 $a Cham : $b Springer Nature Switzerland : $b Imprint: Humana, $c 2024.
300 $a viii, 372 p. : $b ill. (some col.), digital ; $c 24 cm.
347 $a text file $b PDF $2 rda
490 1 $a Cancer drug discovery and development, $x 2196-9914
505 0 $a Preface -- Autophagy and Reactive Oxygen Species in Cancer: An Introduction -- Reactive Oxygen Species (ROS) and Cancer -- Unveiling Therapeutic Targets: Targeting Mitochondrial ROS for Anticancer Therapy -- Molecular Mechanisms of Autophagy Regulation in Cancer -- Autophagy and multi-drug resistance in cancer -- Interplay between Autophagy and Reactive Oxygen Species (ROS) -- Autophagy, Reactive Oxygen Species and Tumorigenesis -- Role of Autophagy and Oxidative Stress in Cancer Metastasis -- Autophagy-targeted Nanoparticles for the Treatment of Cancer -- Autophagy: A Critical Link between Immune Response and Cancer Progression -- Interplay between Autophagy and Apoptosis in Cancer: Mechanisms and Therapeutic Implications -- Unraveling the Nexus: Mitochondrial Oxidative Stress, Tumour Microenvironment, and Escape from Immune Surveillance -- Current Strategies for Targeting Autophagy and ROS for Cancer Treatment -- Exploring the Potential of Dietary Phytochemicals in Cancer Therapeutics: Modulating Apoptosis and Autophagy -- Clinical Trials and Future Prospects of Autophagy and ROS in Cancer -- Index.
520 $a Autophagy is a catabolic process that eliminates damaged and faulty cellular components via lysosomes. It responds to adverse circumstances like nutritional deficiency, hypoxia, and oxidative damage. Reactive oxygen species (ROS) cause oxidative stress, which is a multidimensional chemical that drives various pathophysiological diseases, including cancer. In addition, the autophagy process has a double role, first preventing tumour formation, but later fostering tumour progression. A growing body of research suggests that autophagy and ROS have a complex interplay in which they can either prevent cancer growth or enhance disease genesis. While a combination of autophagy inhibitor and cytotoxic medicines is now being used in cancer treatment, investigating the potential of autophagy inhibitors for overcoming resistance to different anticancer medications and how this relates to the control of cancer micro environmental stressors raises several questions. Autophagy's dual functions as a safeguarding and cytotoxic process have drawn attention to its significance in the development of cancer.
650 0 $a Cancer $x Molecular aspects. $3 221221
650 0 $a Cell death. $3 193735
650 0 $a Lysosomes. $3 193679
650 0 $a Active oxygen $x Physiological effect. $3 785783
650 1 4 $a Cell Death. $3 667149
650 2 4 $a Cancer Therapy. $3 915060
650 2 4 $a Pharmacology. $3 218135
700 1 $a Mishra, Neeraj. $3 949458
700 1 $a Kaundal, Ravinder Kumar. $3 980418
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
830 0 $a Cancer drug discovery and development. $3 557535
856 4 0 $u https://doi.org/10.1007/978-3-031-66421-2
950 $a Biomedical and Life Sciences (SpringerNature-11642)