國立高雄大學圖資館 |

登入

回首頁

COVID-19-Related Maternal Mortality and Morbidity in Brazil: An Exploration of Individual, Municipal, and State Factors /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	COVID-19-Related Maternal Mortality and Morbidity in Brazil: An Exploration of Individual, Municipal, and State Factors /Mary Catherine Cambou.
作者:	Cambou, Mary Catherine,
面頁冊數:	1 electronic resource (113 pages)
附註:	Source: Dissertations Abstracts International, Volume: 85-09, Section: A.
附註:	Advisors: Macinko, James Committee members: Comulada, Warren S.; Moucheraud, Corrina; Nielsen-Saines, Karin.
Contained By:	Dissertations Abstracts International85-09A.
標題:	Public health.
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30993656
ISBN:	9798381744286

COVID-19-Related Maternal Mortality and Morbidity in Brazil: An Exploration of Individual, Municipal, and State Factors /
Cambou, Mary Catherine,

COVID-19-Related Maternal Mortality and Morbidity in Brazil: An Exploration of Individual, Municipal, and State Factors /Mary Catherine Cambou. - 1 electronic resource (113 pages)

Source: Dissertations Abstracts International, Volume: 85-09, Section: A.

Persons infected with SARS-CoV-2 during pregnancy are at increased risk of severe COVID-19, including hospitalization, mechanical ventilation, and death. The effects of the pandemic on maternal mortality and morbidity in Brazil, a country disproportionately impacted by COVID-19, have not been well-characterized. We set out to quantify the effect of the COVID-19 pandemic on maternal mortality in Brazil, as well as identify individual, municipal, and state factors that impacted COVID-19-related maternal mortality and morbidity during the pandemic. Using publicly-available databases through the Brazilian Ministry of Health, we estimated 4,995 maternal deaths from January 1, 2020 to December 31, 2021. Using two complementary forecast models, we demonstrated that the observed maternal mortality ratio (MMR) in 2021 was more than double the predicted MMR based on historical maternal mortality data. From January 1, 2021 to December 31, 2021, there were 10,435 pregnant or postpartum persons hospitalized with COVID-19 in Brazil, of which 1,059 (10.1%) resulted in death. Using a random effects model, a single dose of an approved COVID-19 vaccine prior to hospitalization reduced the odds of maternal death by 66%, and estimated state vaccine coverage >90% reduced the odds of maternal death by 89%. Among this hospitalized population, 3,055 individuals required an intensive care unit (ICU) admission. Using nested logistic regression models (LRMs) and multilevel models (MLMs) to incorporate both individual-level and municipal-level factors, we found that COVID-19 vaccination reduced the odds of maternal ICU admission by 38%. Municipal-level health factors, including high family health strategy coverage and ICU bed rates, were not significantly associated with protection against ICU admission when controlling for clustering in the LRM, or in the MLM with inclusion of municipal-level factors. The national COVID-19 vaccination campaign, including targeting pregnant and postpartum individuals, should remain a cornerstone of the Brazilian public health armamentarium in efforts to reduce the national MMR, and protect against maternal death and ICU admissions due to COVID-19.

English

ISBN: 9798381744286Subjects--Topical Terms:

209444
Public health.
Subjects--Index Terms:

COVID-19

COVID-19-Related Maternal Mortality and Morbidity in Brazil: An Exploration of Individual, Municipal, and State Factors /
LDR:03777nmm a22004573i 4500 001 676282
005 20250420214334.5
006 m o d
007 cr|nu||||||||
008 250901s2024 miu||||||m |||||||eng d
020 $a 9798381744286
035 $a (MiAaPQD)AAI30993656
035 $a AAI30993656
040 $a MiAaPQD $b eng $c MiAaPQD $e rda
100 1 $a Cambou, Mary Catherine, $e author. $3 990030
245 1 0 $a COVID-19-Related Maternal Mortality and Morbidity in Brazil: An Exploration of Individual, Municipal, and State Factors / $c Mary Catherine Cambou.
264 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2024
300 $a 1 electronic resource (113 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertations Abstracts International, Volume: 85-09, Section: A.
500 $a Advisors: Macinko, James Committee members: Comulada, Warren S.; Moucheraud, Corrina; Nielsen-Saines, Karin.
502 $b Ph.D. $c University of California, Los Angeles $d 2024.
520 $a Persons infected with SARS-CoV-2 during pregnancy are at increased risk of severe COVID-19, including hospitalization, mechanical ventilation, and death. The effects of the pandemic on maternal mortality and morbidity in Brazil, a country disproportionately impacted by COVID-19, have not been well-characterized. We set out to quantify the effect of the COVID-19 pandemic on maternal mortality in Brazil, as well as identify individual, municipal, and state factors that impacted COVID-19-related maternal mortality and morbidity during the pandemic. Using publicly-available databases through the Brazilian Ministry of Health, we estimated 4,995 maternal deaths from January 1, 2020 to December 31, 2021. Using two complementary forecast models, we demonstrated that the observed maternal mortality ratio (MMR) in 2021 was more than double the predicted MMR based on historical maternal mortality data. From January 1, 2021 to December 31, 2021, there were 10,435 pregnant or postpartum persons hospitalized with COVID-19 in Brazil, of which 1,059 (10.1%) resulted in death. Using a random effects model, a single dose of an approved COVID-19 vaccine prior to hospitalization reduced the odds of maternal death by 66%, and estimated state vaccine coverage >90% reduced the odds of maternal death by 89%. Among this hospitalized population, 3,055 individuals required an intensive care unit (ICU) admission. Using nested logistic regression models (LRMs) and multilevel models (MLMs) to incorporate both individual-level and municipal-level factors, we found that COVID-19 vaccination reduced the odds of maternal ICU admission by 38%. Municipal-level health factors, including high family health strategy coverage and ICU bed rates, were not significantly associated with protection against ICU admission when controlling for clustering in the LRM, or in the MLM with inclusion of municipal-level factors. The national COVID-19 vaccination campaign, including targeting pregnant and postpartum individuals, should remain a cornerstone of the Brazilian public health armamentarium in efforts to reduce the national MMR, and protect against maternal death and ICU admissions due to COVID-19.
546 $a English
590 $a School code: 0031
650 4 $a Public health. $3 209444
650 4 $a Health sciences. $3 795394
650 4 $a Immunology. $3 189152
650 4 $a Public policy. $3 280699
653 $a COVID-19
653 $a Maternal death
653 $a Maternal morbidity
653 $a Maternal mortality
653 $a Vaccines
690 $a 0573
690 $a 0566
690 $a 0982
690 $a 0454
690 $a 0630
710 2 $a University of California, Los Angeles. $b Health Policy and Management 007I. $e degree granting institution. $3 990031
720 1 $a Macinko, James $e degree supervisor.
773 0 $t Dissertations Abstracts International $g 85-09A.
790 $a 0031
791 $a Ph.D.
792 $a 2024
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30993656