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Gold Nanorod-based Assemblies and Co...

Arizona State University.

Gold Nanorod-based Assemblies and Composites Cancer Therapeutics, Sensors and Tissue Engineering Materials.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Gold Nanorod-based Assemblies and Composites Cancer Therapeutics, Sensors and Tissue Engineering Materials.
Author:	Huang, Huang-Chiao.
Description:	250 p.
Notes:	Source: Dissertation Abstracts International, Volume: 73-08(E), Section: B.
Notes:	Adviser: Kaushal Rege.
Contained By:	Dissertation Abstracts International73-08B(E).
Subject:	Engineering, Biomedical.
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3504103
ISBN:	9781267280404

Gold Nanorod-based Assemblies and Composites Cancer Therapeutics, Sensors and Tissue Engineering Materials.
Huang, Huang-Chiao.

Gold Nanorod-based Assemblies and Composites Cancer Therapeutics, Sensors and Tissue Engineering Materials. - 250 p.

Source: Dissertation Abstracts International, Volume: 73-08(E), Section: B.

Thesis (Ph.D.)--Arizona State University, 2012.

Gold nanoparticles as potential diagnostic, therapeutic and sensing systems have a long history of use in medicine, and have expanded to a variety of applications. Gold nanoparticles are attractive in biological applications due to their unique optical, chemical and biological properties. Particularly, gold nanorods (GNRs) are increasingly used due to superior optical property in the near infrared (NIR) window. Light absorbed by the nanorod can be dissipated as heat efficiently or re-emitted by the particle. However, the limitations for clinical translation of gold nanorods include low yields, poor stability, depth-restricted imaging, and resistance of cancer cells to hyperthermia, are severe. A novel high-throughput synthesis method was employed to significantly increase in yields of solid and porous gold nanorods/wires. Stable functional nanoassemblies and nanomaterials were generated by interfacing gold nanorods with a variety of polymeric and polypeptide-based coatings, resulting in unique properties of polymer-gold nanorod assemblies and composites. Here the use of these modified gold nanorods in a variety of applications including optical sensors, cancer therapeutics, and nanobiomaterials were described.

ISBN: 9781267280404Subjects--Topical Terms:

227004
Engineering, Biomedical.

Gold Nanorod-based Assemblies and Composites Cancer Therapeutics, Sensors and Tissue Engineering Materials.
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502 $a Thesis (Ph.D.)--Arizona State University, 2012.
520 $a Gold nanoparticles as potential diagnostic, therapeutic and sensing systems have a long history of use in medicine, and have expanded to a variety of applications. Gold nanoparticles are attractive in biological applications due to their unique optical, chemical and biological properties. Particularly, gold nanorods (GNRs) are increasingly used due to superior optical property in the near infrared (NIR) window. Light absorbed by the nanorod can be dissipated as heat efficiently or re-emitted by the particle. However, the limitations for clinical translation of gold nanorods include low yields, poor stability, depth-restricted imaging, and resistance of cancer cells to hyperthermia, are severe. A novel high-throughput synthesis method was employed to significantly increase in yields of solid and porous gold nanorods/wires. Stable functional nanoassemblies and nanomaterials were generated by interfacing gold nanorods with a variety of polymeric and polypeptide-based coatings, resulting in unique properties of polymer-gold nanorod assemblies and composites. Here the use of these modified gold nanorods in a variety of applications including optical sensors, cancer therapeutics, and nanobiomaterials were described.
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790 1 0 $a Vogt, Bryan $e committee member
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