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Sigma receptorstheir role in disease...

Smith, Sylvia B.

Sigma receptorstheir role in disease and as therapeutic targets /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Sigma receptorsedited by Sylvia B. Smith, Tsung-Ping Su.
Reminder of title:	their role in disease and as therapeutic targets /
other author:	Smith, Sylvia B.
Published:	Cham :Springer International Publishing :2017.
Description:	xiii, 312 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Nervous systemDegeneration.
Online resource:	http://dx.doi.org/10.1007/978-3-319-50174-1
ISBN:	9783319501741$q(electronic bk.)

Sigma receptorstheir role in disease and as therapeutic targets /
Sigma receptorstheir role in disease and as therapeutic targets /[electronic resource] :edited by Sylvia B. Smith, Tsung-Ping Su. - Cham :Springer International Publishing :2017. - xiii, 312 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.9640065-2598 ;. - Advances in experimental medicine and biology ;946..

Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types. It's putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer's disease, Parkinson's disease, Huntington's disease, pain, drug addiction and locomotor activity. Their roles in possible treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors. Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein.

ISBN: 9783319501741$q(electronic bk.)

Standard No.: 10.1007/978-3-319-50174-1doiSubjects--Topical Terms:

195201
Nervous system
--Degeneration.

LC Class. No.: RM301.41

Dewey Class. No.: 615.7

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