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Transcriptome analysisintroduction a...

Cellerino, Alessandro.

Transcriptome analysisintroduction and examples from the neurosciences /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Transcriptome analysisby Alessandro Cellerino, Michele Sanguanini.
Reminder of title:	introduction and examples from the neurosciences /
Author:	Cellerino, Alessandro.
other author:	Sanguanini, Michele.
Published:	Pisa :Scuola Normale Superiore :2018.
Description:	xiv, 188 p. :digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Bioinformatics.
Online resource:	http://dx.doi.org/10.1007/978-88-7642-642-1
ISBN:	9788876426421$q(electronic bk.)

Transcriptome analysisintroduction and examples from the neurosciences /
Cellerino, Alessandro.

Transcriptome analysisintroduction and examples from the neurosciences /[electronic resource] :by Alessandro Cellerino, Michele Sanguanini. - Pisa :Scuola Normale Superiore :2018. - xiv, 188 p. :digital ;24 cm. - CRM series ;17. - CRM series ;13..

Preface -- Introduction: why study transcriptomics? -- 1. Data distribution and visualisation -- 2. Next-generation RNA sequencing -- 3. RNA-seq raw data processing -- 4. Differentially expressed gene detection & analysis -- 5. Unbiased clustering methods -- 6. Knowledge-based clustering methods -- 7. Network analysis -- 8. Mesoscale transcriptome analysis -- 9. Microscale transcriptome analysis -- Bibliography -- Index.

The goal of this book is to be an accessible guide for undergraduate and graduate students to the new field of data-driven biology. Next-generation sequencing technologies have put genome-scale analysis of gene expression into the standard toolbox of experimental biologists. Yet, biological interpretation of high-dimensional data is made difficult by the lack of a common language between experimental and data scientists. By combining theory with practical examples of how specific tools were used to obtain novel insights in biology, particularly in the neurosciences, the book intends to teach students how to design, analyse, and extract biological knowledge from transcriptome sequencing experiments. Undergraduate and graduate students in biomedical and quantitative sciences will benefit from this text as well as academics untrained in the subject.

ISBN: 9788876426421$q(electronic bk.)

Standard No.: 10.1007/978-88-7642-642-1doiSubjects--Topical Terms:

194415
Bioinformatics.

LC Class. No.: QH455 / .C455 2018

Dewey Class. No.: 570.285

Transcriptome analysisintroduction and examples from the neurosciences /
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505 0 $a Preface -- Introduction: why study transcriptomics? -- 1. Data distribution and visualisation -- 2. Next-generation RNA sequencing -- 3. RNA-seq raw data processing -- 4. Differentially expressed gene detection & analysis -- 5. Unbiased clustering methods -- 6. Knowledge-based clustering methods -- 7. Network analysis -- 8. Mesoscale transcriptome analysis -- 9. Microscale transcriptome analysis -- Bibliography -- Index.
520 $a The goal of this book is to be an accessible guide for undergraduate and graduate students to the new field of data-driven biology. Next-generation sequencing technologies have put genome-scale analysis of gene expression into the standard toolbox of experimental biologists. Yet, biological interpretation of high-dimensional data is made difficult by the lack of a common language between experimental and data scientists. By combining theory with practical examples of how specific tools were used to obtain novel insights in biology, particularly in the neurosciences, the book intends to teach students how to design, analyse, and extract biological knowledge from transcriptome sequencing experiments. Undergraduate and graduate students in biomedical and quantitative sciences will benefit from this text as well as academics untrained in the subject.
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