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Molecular diagnosis and targeting fo...

Isonishi, Seiji.

Molecular diagnosis and targeting for gynecologic malignancy

Record Type:	Electronic resources : Monograph/item
Title/Author:	Molecular diagnosis and targeting for gynecologic malignancyedited by Seiji Isonishi, Yoshihiro Kikuchi.
other author:	Isonishi, Seiji.
Published:	Singapore :Springer Singapore :2021.
Description:	viii, 165 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Generative organs, FemaleCancer
Online resource:	https://doi.org/10.1007/978-981-33-6013-6
ISBN:	9789813360136$q(electronic bk.)

Molecular diagnosis and targeting for gynecologic malignancy
Molecular diagnosis and targeting for gynecologic malignancy[electronic resource] /edited by Seiji Isonishi, Yoshihiro Kikuchi. - Singapore :Springer Singapore :2021. - viii, 165 p. :ill., digital ;24 cm. - Current human cell research and applications,2522-073X. - Current human cell research and applications..

1 Cancer Stem Cells in gynecologic cancer -- 2 Patient-derived xenograft models in gynaecological malignancies -- 3 Cancer genomic profiling of gynecological malignancies by Todai OncoPanel, a twin DNA and RNA panel -- 4 Investigating the molecular carcinogenesis of ovarian high-grade serous cancer -- 5 The role of G protein-coupled receptor signaling in gynecologic malignancy -- 6 Tailor-made therapy according genetic alteration in epithelial ovarian cancers -- 7 Signaling and drug resistance -- 8 Molecular analysis in endometrial carcinoma -- 9 Molecular Landscape in Ovarian Clear Cell Carcinoma -- 10 Molecular pathology and clinicopathological significance of endometrial carcinoma -- 11 Novel approach for therapeutics of cervical cancer based on HPV-associated carcinogenesis at the cervix -- 12 Hereditary gynecological malignancy and molecular features.

This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment, exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.

ISBN: 9789813360136$q(electronic bk.)

Standard No.: 10.1007/978-981-33-6013-6doiSubjects--Topical Terms:

895413
Generative organs, Female
--Cancer

LC Class. No.: RC280.G5 / M65 2021

Dewey Class. No.: 616.994606

Molecular diagnosis and targeting for gynecologic malignancy
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505 0 $a 1 Cancer Stem Cells in gynecologic cancer -- 2 Patient-derived xenograft models in gynaecological malignancies -- 3 Cancer genomic profiling of gynecological malignancies by Todai OncoPanel, a twin DNA and RNA panel -- 4 Investigating the molecular carcinogenesis of ovarian high-grade serous cancer -- 5 The role of G protein-coupled receptor signaling in gynecologic malignancy -- 6 Tailor-made therapy according genetic alteration in epithelial ovarian cancers -- 7 Signaling and drug resistance -- 8 Molecular analysis in endometrial carcinoma -- 9 Molecular Landscape in Ovarian Clear Cell Carcinoma -- 10 Molecular pathology and clinicopathological significance of endometrial carcinoma -- 11 Novel approach for therapeutics of cervical cancer based on HPV-associated carcinogenesis at the cervix -- 12 Hereditary gynecological malignancy and molecular features.
520 $a This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment, exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.
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