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Cardiovascular Autonomic Regulation and Exercise in Parkinson's Disease /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Cardiovascular Autonomic Regulation and Exercise in Parkinson's Disease /Erin Marie Suttman.
作者:	Suttman, Erin Marie,
面頁冊數:	1 electronic resource (134 pages)
附註:	Source: Dissertations Abstracts International, Volume: 87-04, Section: B.
附註:	Advisors: Dibble, Leland Eric Committee members: Gappmaier, Eduard; Fino, Peter C.; Cortez, Melissa Marie; Amann, Markus; Broxterman, Ryan Michael.
Contained By:	Dissertations Abstracts International87-04B.
標題:	Physiology.
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=32117283
ISBN:	9798297641419

Cardiovascular Autonomic Regulation and Exercise in Parkinson's Disease /
Suttman, Erin Marie,

Cardiovascular Autonomic Regulation and Exercise in Parkinson's Disease /Erin Marie Suttman. - 1 electronic resource (134 pages)

Source: Dissertations Abstracts International, Volume: 87-04, Section: B.

As a physiological stressor, exercise requires the parasympathetic and sympathetic branches of the autonomic nervous system coordinate adjustments to various functions, like heart rate, vascular tone, and respiration, to meet the increased metabolic demand of active muscle. Parkinson's disease (PD) is known to effect both the peripheral and central nervous system structures involved in cardiovascular regulation, and arterial baroreflex dysfunction (e.g., orthostatic hypotension), is a common manifestation of the impairments in cardiovascular reflex arcs in PD. Additionally, a "blunted" or diminished heart rate and blood pressure response to exercise has been observed during studies of exercise testing in people with PD, which can contribute to exercise intolerance and fatigue. Both examples demonstrate the autonomic impairments related to PD, yet how these impairments in arterial baroreflex function and a blunted cardiovascular response to exercise may be related to one another is not well understood. The relationship between these PD-related impairments in cardiovascular regulation in response to orthostasis and exercise may provide insight into presentations of exercise intolerance and contributions to the fatigue-deconditioning cycle common in neurological disorders. This is particularly important due to the critical role that exercise plays in improving symptom burden and potentially slowing disease progression in people with PD. By exploring these areas, the work presented in this dissertation will discuss the response to exercise in the context of individuals with PD who experience orthostatic hypotension. Understanding these interactions will help to improve exercise tolerance and develop more personalized exercise prescription with the goal of improving patient outcomes and health-related quality of life.

English

ISBN: 9798297641419Subjects--Topical Terms:

192980
Physiology.
Subjects--Index Terms:

Autonomic dysfunction

Cardiovascular Autonomic Regulation and Exercise in Parkinson's Disease /
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